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Scientific Articles

Aminoacyl tRNA synthetases as malarial drug targets: a comparative bioinformatics study

February 6, 2019 - 15:50 -- Open Access
Author(s): 
Dorothy Wavinya Nyamai and Özlem Tastan Bishop
Reference: 
Malaria Journal 2019 18:34, 6 February 2019

This study showed that, despite, functional and structural conservation, Plasmodium aaRSs have key differences from the human homologues.

Effects of the removal or reduction in density of the malaria mosquito, Anopheles gambiae s.l., on interacting predators and competitors in local ecosystems

February 6, 2019 - 15:41 -- Open Access
Author(s): 
C. M. Collins, J. A. S. Bonds, M. M. Quinlan, J. D. Mumford
Reference: 
Medical and Veterinary Entomology, Volume33, Issue1 March 2019, Pages 1-15

New genetic control methods for mosquitoes may reduce vector species without direct effects on other species or the physical environment common with insecticides or drainage.

NOT Open Access | Fixed dose combinations of anti‐tubercular, antimalarial and antiretroviral medicines on the Indian market: critical analysis of ubiquity, sales and regulatory status

February 6, 2019 - 15:40 -- NOT Open Access
Author(s): 
Virendra S. Ligade, Tanmay M. Thakar, Swapnil J. Dengale
Reference: 
Tropical Medicine & International Health Volume24, Issue2 February 2019 Pages 238-246

A large proportion of FDC formulations available in India has never been approved by CDSCO, hence raising the doubts about their safety and efficacy.

NOT Open Access | Pathological and molecular characterization of avian malaria in captive Magellanic penguins (Spheniscus magellanicus) in South America

February 6, 2019 - 15:39 -- NOT Open Access
Author(s): 
Paula Augusto Taunde, Matheus Viezzer Bianchi, Lívia Perles, Fernando Soares da Silva, Tainã Normanton Guim, Renan Alves Stadler, Marcos Rogério André, David Driemeier & Saulo Petinatti Pavarini
Reference: 
Parasitology Research February 2019, Volume 118, Issue 2, pp 599–606

Avian malaria is a mosquito-borne disease that affects multiple avian species and is caused by protozoans of the genus Plasmodium.

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NOT Open Access | Human erythrocyte band 3 is a host receptor for Plasmodium falciparum glutamic acid–rich protein

February 6, 2019 - 15:33 -- NOT Open Access
Tags: 
Author(s): 
Haifa Almukadi, Christopher Schwake, Maima M. Kaiser, D. C. Ghislaine Mayer, James Schiemer, Michael R. Baldwin, Shreeya Hegde, Yunzhe Lu, Toshihiko Hanada and Athar H. Chishti
Reference: 
Blood 2019 133:470-480

Malaria remains a major global threat to human health and economic development.

NOT Open Access | Validity and reliability of methods to microscopically detect and quantify malaria parasitaemia

February 6, 2019 - 15:31 -- NOT Open Access
Tags: 
Author(s): 
Johannes Mischlinger, Paul Pitzinger, Michael Ramharter, et al.
Reference: 
Tropical Medicine & International Health Volume23, Issue9 September 2018, Pages 980-991

The LAMBA has higher validity than the sWHO and may therefore be preferable in resource‐limited settings without access to routine WBC‐evaluation.

Organization: 

NOT Open Access | Population Pharmacokinetics of Mefloquine Intermittent Preventive Treatment for Malaria in Pregnancy in Gabon

February 6, 2019 - 15:24 -- NOT Open Access
Tags: 
Author(s): 
Michael Ramharter, Matthias Schwab, Thorsten Lehr, et al.
Reference: 
Antimicrob. Agents Chemother. January 2019 63:e01113-18

Mefloquine was evaluated as an alternative for intermittent preventive treatment of malaria in pregnancy (IPTp) due to increasing resistance against the first-line drug sulfadoxine-pyrimethamine (SP).

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NOT Open Access | Modeling Prevention of Malaria and Selection of Drug Resistance with Different Dosing Schedules of Dihydroartemisinin-Piperaquine Preventive Therapy during Pregnancy in Uganda

February 6, 2019 - 15:20 -- NOT Open Access
Tags: 
Author(s): 
Erika Wallender, Nan Zhang, Rada M. Savic, et al.
Reference: 
Antimicrob. Agents Chemother. January 2019 63:e01393-18

Dihydroartemisinin-piperaquine (DHA-PQ) is under study for intermittent preventive treatment during pregnancy (IPTp), but it may accelerate selection for drug resistance.

Drug Interactions between Dolutegravir and Artemether-Lumefantrine or Artesunate-Amodiaquine

February 5, 2019 - 17:54 -- Open Access
Author(s): 
Stephen I. Walimbwa, Mohammed Lamorde, Saye H. Khoo, et al.
Reference: 
Antimicrob. Agents Chemother. January 2019 63:e01310-18

Across sub-Saharan Africa, patients with HIV on antiretrovirals often get malaria and need cotreatment with artemisinin-containing therapies.

How can interventions that target forest-goers be tailored to accelerate malaria elimination in the Greater Mekong Subregion? A systematic review of the qualitative literature

February 5, 2019 - 16:23 -- Open Access
Author(s): 
Stephanie D. Nofal, Thomas J. Peto, Bipin Adhikari, Rupam Tripura, James Callery, Thanh Mai Bui, Lorenz von Seidlein and Christopher Pell
Reference: 
Malaria Journal 2019 18:32, 1 February 2019

A more detailed characterization of forest activities is needed but research on this topic raises methodological challenges.

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