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Scientific Articles

Using mixed effects logistic regression models for complex survey data on malaria rapid diagnostic test results

December 6, 2018 - 16:46 -- Open Access
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Author(s): 
Chigozie Louisa J. Ugwu and Temesgen T. Zewotir
Reference: 
Malaria Journal 2018 17:453, 5 December 2018

Improvement of socio-economic development and quality of life is paramount to achieving malaria free Nigeria.

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Treatments used for malaria in young Ethiopian children: a retrospective study

December 6, 2018 - 16:43 -- Open Access
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Author(s): 
Abyot Endale Gurmu, Teresa Kisi, Habteweld Shibru, Bertrand Graz and Merlin Willcox
Reference: 
Malaria Journal 2018 17:451, 5 December 2018

In this study, only 30% of children took the recommended first-line treatment.

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NOT Open Access | Exposure to Plasmodium vivax is associated with the increased expression of exhaustion markers on γδ T lymphocytes

December 5, 2018 - 16:32 -- NOT Open Access
Author(s): 
Dimpu Gogoi, Dipankar Biswas, Biswajyoti Borkakoty, Jagadish Mahanta
Reference: 
Parasite Immunology Volume40, Issue12 December 2018 e12594

Gamma delta (γδ) T cells exhibit potent anti‐Plasmodium activity but are also implicated in the immunopathology of malaria.

A forward genetic screen reveals a primary role for Plasmodium falciparum Reticulocyte Binding Protein Homologue 2a and 2b in determining alternative erythrocyte invasion pathways

December 5, 2018 - 16:30 -- Open Access
Author(s): 
Susana Campino, Alejandro Marin-Menendez, Julian C. Rayner, et al.
Reference: 
PLoS Pathog 14(11): e1007436

Invasion of human erythrocytes is essential for Plasmodium falciparum parasite survival and pathogenesis, and is also a complex phenotype.

Inhibition of JNK signaling in the Asian malaria vector Anopheles stephensi extends mosquito longevity and improves resistance to Plasmodium falciparum infection

December 5, 2018 - 16:29 -- Open Access
Author(s): 
Lattha Souvannaseng, Lewis Vibul Hun, Shirley Luckhart, et al.
Reference: 
PLoS Pathog 14(11): e1007418

Malaria is a global health concern caused by infection with Plasmodium parasites.

NOT Open Access | New Evidence for Hypnozoite-Independent Plasmodium vivax Malarial Recurrences

December 5, 2018 - 16:01 -- NOT Open Access
Author(s): 
Miles B. Markus
Reference: 
Trends in Parasitology Volume 34, Issue 12, P1015-1016, December 01, 2018

Information provided in recent, related papers has wide-ranging implications concerning, inter alia, the transmission of malaria, drug treatment, and eradication of the disease.

Malaria case investigation with reactive focal testing and treatment: operational feasibility and lessons learned from low and moderate transmission areas in Amhara Region, Ethiopia

December 5, 2018 - 15:55 -- Open Access
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Author(s): 
Pooja Bansil, Asnakew K. Yeshiwondim, Asefaw Getachew, et al.
Reference: 
Malaria Journal 2018 17:449, 4 December 2018

Three types of malaria transmission patterns were observed: (1) low importation and low local transmission; (2) high importation and low local transmission; and, (3) low importation and high local transmission.

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Accuracy of One Step malaria rapid diagnostic test (RDT) in detecting Plasmodium falciparum placental malaria infection in women living in Yaoundé, Cameroon

December 5, 2018 - 15:53 -- Open Access
Author(s): 
Rosette Megnekou, Jean Claude Djontu, Benderli C. Nana, Jude D. Bigoga, Maurice Fotso, Balotin Fogang and Rose F. G. Leke
Reference: 
Malaria Journal 2018 17:450, 4 December 2018

These results depict One Step malaria HRP-II RDT to be better in detecting placental P. falciparum infection in pregnant women compared to Giemsa-stained peripheral thick blood smear.

Medical Treatment: 

Diversity analysis of MSP1 identifies conserved epitope organization in block 2 amidst high sequence variability in Indian Plasmodium falciparum isolates

December 5, 2018 - 15:50 -- Open Access
Author(s): 
Sharmistha Ghoshal, Pragya Gajendra, Sumana Datta Kanjilal, Mitashree Mitra and Sanghamitra Sengupta
Reference: 
Malaria Journal 2018 17:447, 3 December 2018

Present data indicates that natural selection and transmission intensity jointly play a role in controlling allelic diversity of MSP1 in Indian parasite isolates.

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