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Scientific Articles

NOT Open Access | Down‐selecting circumsporozoite protein‐based malaria vaccine: A comparison of malaria sporozoite challenge model

April 16, 2019 - 08:12 -- NOT Open Access
Author(s): 
Fitri Amelia, Mitsuhiro Iyori, Talha Bin Emran, Daisuke S. Yamamoto, Kento Genshi, Hiromu Otsuka, Yutaro Onoue, Yenni Yusuf, Ashekul Islam, Shigeto Yoshida
Reference: 
Parasite Immunology Volume41, Issue5 May 2019 e12624

Plasmodium falciparum circumsporozoite protein (PfCSP) is the main target antigen in development of pre‐erythrocytic malaria vaccines.

Social determinants of malaria in an endemic area of Indonesia

April 14, 2019 - 17:17 -- Open Access
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Author(s): 
Hamzah Hasyim, Pat Dale, David A. Groneberg, Ulrich Kuch and Ruth Müller
Reference: 
Malaria Journal 2019 18:134, 12 April 2019

Factors that can be managed and would favour malaria elimination include a range of prevention behaviours at the individual level and using the networks at the community level of primary healthcare centres.

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Comparison of malaria treatment outcome of generic and innovator’s anti-malarial drugs containing artemether–lumefantrine combination in the management of uncomplicated malaria amongst Tanzanian children

April 14, 2019 - 17:09 -- Open Access
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Author(s): 
Manase Kilonzi, Omary Minzi, Ritah Mutagonda, Philip Sasi, Appolinary Kamuhabwa and Eleni Aklillu
Reference: 
Malaria Journal 2019 18:133, 11 April 2019

 

The findings of this study indicate that both Artefan® and Coartem® are equivalent and effective in the management of uncomplicated malaria amongst children in the Coast part of Tanzania.

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HSP superfamily of genes in the malaria vector Anopheles sinensis: diversity, phylogenetics and association with pyrethroid resistance

April 14, 2019 - 17:07 -- Open Access
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Author(s): 
Feng-Ling Si, Liang Qiao, Qi-Yi He, Yong Zhou, Zhen-Tian Yan and Bin Chen
Reference: 
Malaria Journal 2019 18:132, 11 April 2019

This study provides the information frame for HSP superfamily of genes, and lays an important basis for the better understanding and further research of HSP function in insect adaptability to diverse environments.

Modification of contact avoidance behaviour associated with pyrethroid resistance in Anopheles sinensis (Diptera: Culicidae)

April 14, 2019 - 17:06 -- Open Access
Author(s): 
Zhengbo He, Jing Zhang, Zongpan Shi, Jingang Liu, Jingjing Zhang, Zhentian Yan and Bin Chen
Reference: 
Malaria Journal 2019 18:131, 11 April 2019

The An. sinensis populations were highly resistant to deltamethrin and exhibited decreased avoidance behaviour.

Distribution of Plasmodium species and assessment of performance of diagnostic tools used during a malaria survey in Southern and Western Provinces of Zambia

April 14, 2019 - 17:03 -- Open Access
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Author(s): 
Lungowe Sitali, John M. Miller, Mulenga C. Mwenda, Daniel J. Bridges, Moonga B. Hawela, Busiku Hamainza, Elizabeth Chizema-Kawesha, Thomas P. Eisele, James Chipeta and Bernt Lindtjørn
Reference: 
Malaria Journal 2019 18:130, 11 April 2019

From the sub-set of survey data analysed, non-falciparum species are present and occurred as mixed infections.

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Genetic variation of avian malaria in the tropical Andes: a relationship with the spatial distribution of hosts

April 14, 2019 - 16:58 -- Open Access
Tags: 
Author(s): 
Diana Lorena Gil-Vargas and Raul Ernesto Sedano-Cruz
Reference: 
Malaria Journal 2019 18:129, 11 April 2019

Spatial analyses revealed that richness and turnover in haemosporidia suggest an association with montane host diversity, according to elevation in the tropical Andes.

Age-dependent increase in antibodies that inhibit Plasmodium falciparum adhesion to a subset of endothelial receptors

April 14, 2019 - 16:41 -- Open Access
Author(s): 
Oumar Attaher, Almahamoudou Mahamar, Michal Fried, et al.
Reference: 
Malaria Journal 2019 18:128, 11 April 2019

Age is associated with increased levels of antibodies that reduce adhesion of children’s IE to three of the ten endothelial receptors evaluated here.

Introgression between Anopheles gambiae and Anopheles coluzzii in Burkina Faso and its associations with kdr resistance and Plasmodium infection

April 14, 2019 - 16:37 -- Open Access
Author(s): 
Mark J. Hanemaaijer, Hannah Higgins, Ipek Eralp, Youki Yamasaki, Norbert Becker, Oscar D. Kirstein, Gregory C. Lanzaro and Yoosook Lee
Reference: 
Malaria Journal 2019 18:127, 11 April 2019

This paper is the first report providing divergence island SNP genotypes for natural population of Burkina Faso and corresponding Plasmodium infection rates.

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African isolates show a high proportion of multiple copies of the Plasmodium falciparum plasmepsin-2 gene, a piperaquine resistance marker

April 14, 2019 - 16:35 -- Open Access
Author(s): 
Didier Leroy, Fiona Macintyre, Didier Ménard, et al.
Reference: 
Malaria Journal 2019 18:126, 10 April 2019

These findings were considered to sharply contrast with the recent description of increased sensitivity to PPQ of Ugandan parasite isolates.

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