Pregnant women and children are the most vulnerable populations for malaria infection. Yet, knowledge of risk, and preventive measures are poor among this population. Using the 2015 Nigeria Malaria Indicator Survey, we applied logit link function to estimate the associations of wealth status, educational attainment, and region of residence with malaria risk knowledge and prevention strategies (using a treated mosquito net and malaria drugs) among 739 Nigerian pregnant women aged 15–49 years.
Plasmodium falciparum proteins involved in vascular endothelial cell adherence are transported to the surface of infected erythrocytes. These proteins are exported through parasite-derived membrane structures within the erythrocyte cytoplasm called Maurer's clefts. Skeleton binding protein 1 (SBP1) is localized in the Maurer's clefts and plays an important role in transporting molecules to the surface of infected erythrocytes.
Membrane transport proteins, also known as transporters, control the movement of ions, nutrients, metabolites, and waste products across the membranes of a cell and are central to its biology. Proteins of this type also serve as drug targets and are key players in the phenomenon of drug resistance.
Exposure to inorganic fertilizer is common for the major malaria vector Anopheles arabiensis, which is closely associated with agricultural activities. The aim of this study was to understand if insecticide susceptible and resistant individuals respond to fertilizer exposure in the same manner. Two laboratory strains, SENN, an insecticide susceptible strain, and SENN‐DDT, an insecticide resistant strain selected strain selected from SENN, were used in this study. Both strains were exposed to one of three concentrations of a combination nitrogen‐phosphorus‐potassium (NPK) inorganic fertilizer, as well as nitrogenous (urea), phosphorus (superphosphate) and kaelic (potassium chloride, KCl) elemental fertilizer. The time to pupation was monitored, adult longevity was assessed and the insecticide tolerance of adults was determined. The effect of elemental fertilizers on ovipositioning site choice was also assessed.
Ivermectin is a potential new vector control tool to reduce malaria transmission. Mosquitoes feeding on a bloodmeal containing ivermectin have a reduced lifespan, meaning they are less likely to live long enough to complete sporogony and become infectious. We aimed to estimate the effect of ivermectin on malaria transmission in various scenarios of use.
Seven tetracyclic spiro-alkaloids, i.e. glucoerysodine (1), erysodine (2), epi-erythratidine (3), erysovine (4), erythratidine (5), erysotrine (6) and erythraline (7) were isolated from the seeds of Erythrina latissima by means of conventional separation methods and HPLC-DAD-SPE-NMR. Their structures were elucidated by spectroscopic means.
Cerebral malaria (CM) remains a leading cause of mortality and morbidity in children in sub-Saharan Africa. Recent studies using brain magnetic resonance imaging have revealed increased brain volume as a major predictor of death. Similar morphometric predictors of morbidity at discharge are lacking. The aim of this study was to investigate the utility of serial cranial cisternal cerebrospinal fluid (CSF) volume measurements in predicting morbidity at discharge in pediatric CM survivors.
During April–June 2014 in a malaria-endemic rural community close to the city of Iquitos in Peru, we detected evidence of Guaroa virus (GROV) infection in 14 febrile persons, of whom 6 also had evidence of Plasmodium vivax malaria. Cases were discovered through a long-term febrile illness surveillance network at local participating health facilities.
Persistent insecticides sprayed onto house walls, and incorporated into insecticide‐treated bednets, provide long‐acting, cost‐effective control of vector‐borne diseases such as malaria and leishmaniasis. The high concentrations that occur immediately postdeployment may kill both resistant and susceptible insects.
Malaria is an important infectious disease that is transmitted by female mosquitoes of the genus Anopheles infected with parasites of the genus Plasmodium. In this research, it was aimed to contribute to the ongoing studies on malaria control in Antalya.