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Scientific Articles

Comparing the un-comparable: Olyset Plus and Olyset, different malaria impact

December 5, 2018 - 15:48 -- Open Access
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Author(s): 
Ole Skovmand
Reference: 
Malaria Journal 2018 17:446, 30 November 2018

Data published by the World Health Organization (WHO) when evaluating Olyset+ as well of the study of Protopopoff et al. showed that much more permethrin is available on the surface of Olyset+ than on the surface of Olyset and the relatively small and rapidly dwindling dosage of PBO may have nothing to do with the superior effect of Olyset+.

A new approach to gathering pharmaceutical market data to support policy implementation and access to medicines: as demonstrated by malaria medicines in Zambia

December 4, 2018 - 14:49 -- Open Access
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Author(s): 
Renia Coghlan, Peter Stephens, Bernice Mwale and Makomani Siyanga
Reference: 
Malaria Journal 2018 17:444, 29 November 2018

Routine data are important for researchers and policy makers alike.

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Within-population genetic diversity and population structure of Plasmodium knowlesi merozoite surface protein 1 gene from geographically distinct regions of Malaysia and Thailand

December 4, 2018 - 14:47 -- Open Access
Author(s): 
Md Atique Ahmed, Ki-Back Chu, Indra Vythilingam and Fu-Shi Quan
Reference: 
Malaria Journal 2018 17:442, 29 November 2018

This study is the first to report on inter country genetic diversity and population structure of P. knowlesi based on msp1.

Area of exposure and treatment challenges of malaria in Eritrean migrants: a GeoSentinel analysis

December 4, 2018 - 14:46 -- Open Access
Author(s): 
Patricia Schlagenhauf, Martin P. Grobusch, Perry van Genderen, et al.
Reference: 
Malaria Journal 2018 17:443, 29 November 2018

The 146 cases of mainly late onset, sometimes severe, P. vivax malaria in Eritrean migrants described in this multi-site, global analysis reflect the findings of single-centre analyses identified in the literature search.

A multiplex assay for the sensitive detection and quantification of male and female Plasmodium falciparum gametocytes

December 4, 2018 - 14:43 -- Open Access
Author(s): 
Lisette Meerstein-Kessel, Chiara Andolina, Teun Bousemat, et al.
Reference: 
Malaria Journal 2018 17:441, 29 November 2018

Gametocyte densities and their sex ratios can be determined in the presented one-step multiplex assay with higher throughput than single assays.

Dry season occurrence of Anopheles mosquitoes and implications in Jabi Tehnan District, West Gojjam Zone, Ethiopia

December 4, 2018 - 14:38 -- Open Access
Author(s): 
Abebe Animut and Yohannes Negash
Reference: 
Malaria Journal 2018 17:445, 29 November 2018

Streams were prolific breeding habitats of Anopheles mosquitoes followed by ponds and swamps in the dry seasons.

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Outreach training and supportive supervision for malaria case management in Zambia: the effects of focused capacity building on indicators of diagnostic and clinical performance

December 4, 2018 - 14:34 -- Open Access
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Author(s): 
Matt Worges, Nicole Whitehurst, Emanuel Yamo, Hawela Moonga, Joshua Yukich and Luis Benavente
Reference: 
Malaria Journal 2018 17:438, 28 November 2018

The external quality assurance scheme provided periodic representations of clinical and laboratory staff performance.

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Molecular identification of Plasmodium species responsible for malaria reveals Plasmodium vivax isolates in Duffy negative individuals from southwestern Nigeria

December 4, 2018 - 14:32 -- Open Access
Author(s): 
Mary Aigbiremo Oboh, Aida Sadikh Badiane, Godwin Ntadom, Yaye Die Ndiaye, Khadim Diongue, Mamadou Alpha Diallo and Daouda Ndiaye
Reference: 
Malaria Journal 2018 17:439, 28 November 2018

The present study gave the first molecular evidence of P. vivax in Nigeria in Duffy negative individuals.

Challenges for the diagnosis and treatment of malaria in low transmission settings in San Lorenzo, Esmeraldas, Ecuador

December 4, 2018 - 14:28 -- Open Access
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Author(s): 
Mayte Mosquera-Romero, Lina Zuluaga-Idárraga and Alberto Tobón-Castaño
Reference: 
Malaria Journal 2018 17:440, 28 November 2018

The network of diagnostic services for malaria is weak in San Lorenzo, and socio-economic, political and historical factors hinder the implementation of the universal malaria elimination strategy based on diagnosis and treatment.

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NOT Open Access | Synthesis, Biological Evaluation, and Molecular Modeling Studies of Chiral Chloroquine Analogues as Antimalarial Agents

November 28, 2018 - 15:58 -- NOT Open Access
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Author(s): 
Srinivasarao Kondaparla, Utsab Debnath, Awakash Soni, Vasantha Rao Dola, Manish Sinha, Kumkum Srivastava, Sunil K. Puri and Seturam B. Katti
Reference: 
Antimicrob. Agents Chemother. December 2018 62:e02347-17

In a focused exploration, we designed, synthesized, and biologically evaluated chiral conjugated new chloroquine (CQ) analogues with substituted piperazines as antimalarial agents.

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