Data from this study showed that care-seeking in Mozambique remained suboptimal.
A novel real-time PCR-based method to assess P. vivax Pvpm4 gene amplification was developed.
These results highlight the important vector control challenge facing countries with high EIR despite the recent campaigns of bed net distribution.
The results showed that mosquito age and blood feeding status confers increased tolerance to insecticides as blood feeding may be playing an important role in the toxicity of deltamethrin, allowing mosquitoes to rest on insecticide-treated materials despite treatment.
Severe clinical outcomes amongst infants treated with primaquine in Papua were rare.
While the data indicate that changes in landscape due to human activities lead to a reduction in An. cruzii abundance, such changes may increase the contact rate between this species and humans living on the edges of forest fragments where An. cruzii is found.
In this high transmission setting, EPF sampling with rtPCR analysis has satisfactory diagnostic performance in estimation of mean prevalence and prevalence by school upon direct comparison with POC-RDTs.
The critical self-evaluation of programme performance has allowed the KZN malaria programme to plan to address key issues moving forward.
The observed patterns in P. vivax are consistent with a “corridor” where connected endemic areas can sustain a high level of genetic diversity locally and can restore parasite-subdivided populations via migration of infected individuals even after local interventions achieved a substantial reduction of clinical cases.