Streams were prolific breeding habitats of Anopheles mosquitoes followed by ponds and swamps in the dry seasons.
The external quality assurance scheme provided periodic representations of clinical and laboratory staff performance.
The present study gave the first molecular evidence of P. vivax in Nigeria in Duffy negative individuals.
The network of diagnostic services for malaria is weak in San Lorenzo, and socio-economic, political and historical factors hinder the implementation of the universal malaria elimination strategy based on diagnosis and treatment.
In a focused exploration, we designed, synthesized, and biologically evaluated chiral conjugated new chloroquine (CQ) analogues with substituted piperazines as antimalarial agents.
The in vivo antimalarial efficacies of two phosphatidylinositol 4-kinase (PI4K) inhibitors, a 3,5-diaryl-2-aminopyrazine sulfoxide and its corresponding sulfone metabolite, were evaluated in the NOD-scid IL2Rγnull (NSG) murine malaria disease model of Plasmodium falciparum infection.
Antimalarial treatment currently relies on an artemisinin derivative and a longer-acting partner drug.
Plasmodium infection, both for IFN-γ-dependent effector mechanisms and providing B cell helper signals.
Correlating aberrant miRNA levels with imported malaria during the blood stage is required to better understand the in vivo biological and molecular processes that are involved in the response to Plasmodium falciparum infection and to find new biomarkers and diagnosis tools.