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Scientific Articles

NOT Open Access | Changing Molecular Markers of Antimalarial Drug Sensitivity across Uganda

March 5, 2019 - 15:56 -- NOT Open Access
Author(s): 
Victor Asua, Joanna Vinden, Melissa D. Conrad, Jennifer Legac, Simon P. Kigozi, Moses R. Kamya, Grant Dorsey, Samuel L. Nsobya and Philip J. Rosenthal
Reference: 
Antimicrob. Agents Chemother. February 2019 63:e01818-18

The potential spread of antimalarial drug resistance to Africa, in particular for artemisinins and key partner drugs, is a major concern.

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Antibody responses to Plasmodium vivax Duffy binding and Erythrocyte binding proteins predict risk of infection and are associated with protection from clinical Malaria

March 5, 2019 - 15:55 -- Open Access
Author(s): 
Wen-Qiang He, Ahmad Rushdi Shakri, Ivo Mueller, et al.
Reference: 
PLoS Negl Trop Dis 13(2): e0006987

Antibodies to the key parasite invasion ligands PvDBPII and PvEBPII are good correlates of protection against P. vivax malaria in PNG

Acute interstitial nephritis with podocyte foot-process effacement complicating Plasmodium falciparum infection

March 5, 2019 - 15:53 -- Open Access
Author(s): 
Patrick J. Gleeson, John A. O’Regan, Teresa McHale, Helen Tuite, Louise Giblin and Donal Reddan
Reference: 
Malaria Journal 2019 18:58, 1 March 2019

Acute interstitial nephritis and podocyte foot-process effacement might be under-recognized lesions in MARF

The impact of targeted malaria elimination with mass drug administrations on falciparum malaria in Southeast Asia: A cluster randomised trial

February 28, 2019 - 16:00 -- Open Access
Author(s): 
Lorenz von Seidlein, Thomas J. Peto, Nicholas J. White, et al.
Reference: 
PLoS Med 16(2): e1002745

Added to community-based basic malaria control measures, 3 monthly rounds of DP MDA reduced the incidence and prevalence of falciparum malaria over a 1-year period in areas affected by artemisinin resistance.

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Not Open Access | DNA helicase RecQ1 regulates mutually exclusive expression of virulence genes in Plasmodium falciparum via heterochromatin alteration

February 28, 2019 - 15:58 -- NOT Open Access
Author(s): 
Zhou Li, Shigang Yin, Lubin Jiang, et al.
Reference: 
PNAS February 19, 2019 116 (8) 3177-3182

The Plasmodium falciparum var gene family encodes ∼60 surface antigens by which parasites escape the host immune responses via clonal expression of var genes.

An update on glucose-6-phosphate dehydrogenase deficiency in children from Brazzaville, Republic of Congo

February 28, 2019 - 15:48 -- Open Access
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Author(s): 
Nerly Shirère Gampio Gueye, Simon Marie Peko, David Nderu, Felix Koukouikila-Koussounda, Christevy Vouvoungui, Simon Charles Kobawila, Thirumalaisamy P. Velavan and Francine Ntoumi
Reference: 
Malaria Journal 2019 18:57, 28 February 2019

This study gives an update on G6PD deficiency among Congolese children.

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‘The mosquitoes are preparing to attack us’: knowledge and perceptions of communities in south-eastern Tanzania regarding mosquito swarms

February 28, 2019 - 15:46 -- Open Access
Author(s): 
Marceline F. Finda, Emmanuel W. Kaindoa, Anna P. Nyoni and Fredros O. Okumu
Reference: 
Malaria Journal 2019 18:56, 26 February 2019

Majority of the community members recognized presence of mosquito swarms in their communities but did not associate these swarms with mosquito mating.

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Impact of sunlight exposure on the residual efficacy of biolarvicides Bacillus thuringiensis israelensis and Bacillus sphaericus against the main malaria vector, Anopheles gambiae

February 28, 2019 - 15:43 -- Open Access
Author(s): 
Barnabas Zogo, Bertin N’Cho Tchiekoi, Alphonsine A. Koffi, Amal Dahounto, Ludovic P. Ahoua Alou, Roch K. Dabiré, Lamine Baba-Moussa, Nicolas Moiroux and Cédric Pennetier
Reference: 
Malaria Journal 2019 18:55, 26 February 2019

These findings emphasize the impact of environmental variables (e.g., sunlight exposure) on the residual efficacy of Bti and Bs biolarvicides in the field.

Environmental and meteorological factors linked to malaria transmission around large dams at three ecological settings in Ethiopia

February 28, 2019 - 15:42 -- Open Access
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Author(s): 
Solomon Kibret, G. Glenn Wilson, Darren Ryder, Habte Tekie and Beyene Petros
Reference: 
Malaria Journal 2019 18:54, 26 February 2019

This study confirmed that reservoir-associated factors (distance from reservoir shoreline, monthly average reservoir water level, monthly water level change) were important predictors of increased malaria incidence in villages around Ethiopian dams in all elevation settings.

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Environmental and sociodemographic factors associated with household malaria burden in the Congo

February 28, 2019 - 15:40 -- Open Access
Tags: 
Author(s): 
Nlandu Roger Ngatu, Sakiko Kanbara, Shunya Ikeda, et al.
Reference: 
Malaria Journal 2019 18:53, 26 February 2019

This study showed that household size, income, WASH status and rural site were malaria-associated factors.

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