Most malaria endemic regions are co-infested with HIV infection.
We compared results of a malaria rapid diagnostic test (Binax Now® Malaria, Binax-M, Inverness Medical Innovations, Inc., Waltham, MA) performed at rural mobile clinics in Uganda by clinicians evaluating febrile adult HIV patients to thick smear evaluated at a central laboratory by trained microscopists.
An open randomized clinical trial study was carried out to compare efficacy and tolerability of artesunate mefloquine 25 mg/kg body weight (Artequin paediatric) versus artemether lumefantrine (Coartem) in the treatment of uncomplicated Plasmodium falciparum malaria in children.
This is the first report to suggest that the interaction of VEGF and sVEGFR-2 is involved in the host immune response to malarial infection and that malarial parasites induce VEGF secretion from human mast cells.
This study was conducted to investigate the effect of Plasmodium falciparum and intestinal helminth coinfection on maternal anemia and birth outcomes.
The paper provides valuable information on fitness costs to the homozygote susceptible and resistant strains. The authors show that the largest impact is on pupal mortality, while the costs of earlier pupation and smaller adult size are less clear.
The paper provides additional data on the characterization of CSA-binding PfEMP1 domains, implicated in placental malaria, including practical concerns about how to develop an anti-PAM vaccine.
A case report of a fatal case of malaria knowlesi in a formerly healthy 40-year old male, ten days after spending time in the jungle of North Borneo.
A paper that addresses the issue of possible selection of drug resistant parasites in the context of Intermittent Preventive Treatment in infants. Importantly, this study evaluates the impact of the intervention at community level, in a context of a large scale implementation.
Interesting paper aiming at investigating the role and applicability of the molecular drug resistance profiles in community samples in Papua New Guinea.