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Scientific Articles

Longitudinal Survey of Plasmodium falciparum Infection in Vietnam: Characteristics of Antimalarial Resistance and Their Associated Factors

January 14, 2010 - 17:54 -- Kabogo Ndegwa
Author(s): 
Rie Isozumi, Haruki Uemura, Le Duc Dao, Truong Van Hanh, Nguyen Duc Giang, Ha Viet Vien, Bui Quang Phuc, Nguyen Van Tuan, and Shusuke Nakazawa
Reference: 
Journal of Clinical Microbiology, January 2010, p. 70-77, Vol. 48, No. 1

Defining the trend in genotypes related to drug resistance is essential for the control of malaria in Vietnam.

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Open Access | Placental malaria is associated with reduced early life weight development of affected children independent of low birth weight

January 14, 2010 - 12:25 -- Ingeborg van Schayk
Author(s): 
Brigitte Walther, David JC Miles, Sarah Crozier, Pauline Waight, Melba S Palmero, Olubukola Ojuola, Ebrima Touray, Marianne van der Sande, Hilton Whittle, Sarah Rowland-Jones, Katie L Flanagan
Reference: 
Malaria Journal 2010, 9:16 (14 January 2010)

 A study which documents the association of placental malaria with restricted postnatal growth independent of low birthweight, a well-known cause of neonatal and infant mortality.

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Open Access | Prevalence of anopheline species and their Plasmodium infection status in epidemic-prone border areas of Bangladesh

January 14, 2010 - 12:20 -- Ingeborg van Schayk
Author(s): 
Mohammad Shafiul Alam, Md. Gulam Musawwir Khan, Nurunnabi Chaudhury, Sharmina Deloer, Forida Nazib, A Mannan Bangali, Rashidul Haque
Reference: 
Malaria Journal 2010, 9:15 (14 January 2010)

The manuscript contains valuable data on Anopheline species prevalence and their infection status in malaria epidemic-prone area in Bangladesh.

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Open Access | Shift in epitope dominance of IgM and IgG responses to Plasmodium falciparum MSP1 block 4

January 14, 2010 - 12:13 -- Ingeborg van Schayk
Author(s): 
Sandra P Chang, Alexander KK Kayatani, Zilka I Terrientes, Socrates Herrera, Rose GF Leke, Diane W Taylor
Reference: 
Malaria Journal 2010, 9:14 (13 January 2010)

The need to identify biologically relevant and protective peptide sequences from Plasmodium falciparum proteins remains a very important area in malaria vaccine studies.

Open Access | Severe Plasmodium vivax malaria exhibits marked inflammatory imbalance

January 14, 2010 - 12:06 -- Ingeborg van Schayk
Author(s): 
Bruno B Andrade, Antonio Reis-Filho, Sebastiao M Souza-Neto, Jorge Clarencio, Luis MA Camargo, Aldina Barral, Manoel Barral-Netto
Reference: 
Malaria Journal 2010, 9:13 (13 January 2010)

A useful contribution on severe vivax malaria in one municipality of the state of Rondonia in the Brazilian Amazon. This paper is a reminder that there is currently no WHO definition of severe vivax malaria, a disease substantially different from falciparum malaria.

Open Access | Synergistic and Additive Effects of Epigallocatechin Gallate and Digitonin on Plasmodium Sporozoite Survival and Motility

January 14, 2010 - 11:57 -- Ingeborg van Schayk
Author(s): 
Janina K. Hellmann, Sylvia Münter, Michael Wink, Friedrich Frischknecht
Reference: 
PLoS ONE 5(1): e8682

Most medicinal plants contain a mixture of bioactive compounds, including chemicals that interact with intracellular targets and others that can act as adjuvants to facilitate absorption of polar agents across cellular membranes.

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Digestive-vacuole genesis and endocytic processes in the early intraerythrocytic stages of Plasmodium falciparum

January 14, 2010 - 11:49 -- Ingeborg van Schayk
Author(s): 
Nurhidanatasha Abu Bakar, Nectarios Klonis, Eric Hanssen, Cherrine Chan, and Leann Tilley
Reference: 
JCS ePress online publication date 12 Jan 2010

The digestive vacuole of the malaria parasite Plasmodium falciparum is the site of haemoglobin digestion and haem detoxification, and is the target of chloroquine and other antimalarials.

Open Access | Acquisition of antibody isotypes against Plasmodium falciparum blood stage antigens in a birth cohort

January 14, 2010 - 11:31 -- Ingeborg van Schayk
Author(s): 
N. Duah, D. Miles, H. Whittle, D. Conway
Reference: 
Parasite Immunology, Volume 32 Issue 2, Pages 125 - 13

Information on the period during which infants lose their maternally derived antibodies to malaria and begin to acquire naturally their own immune responses against parasite antigens is crucial for understanding when malaria vaccines may be best administered.

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Evidence for Pleistocene Population Divergence and Expansion of Anopheles albimanus in Southern Central America

January 14, 2010 - 11:20 -- Ingeborg van Schayk
Author(s): 
Jose R. Loaiza, Marilyn E. Scott, Eldredge Bermingham, Jose Rovira, AND Jan E. Conn
Reference: 
Am J Trop Med Hyg 2010;82 156-164

The micro-geographic structure of Anopheles albimanus was studied in southern Central America using partial sequences of the mtDNA cytochrome oxidase subunit I gene (COI).

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Quality Assurance of Rapid Diagnostic Tests for Malaria in Routine Patient Care in Rural Tanzania

January 14, 2010 - 11:09 -- Ingeborg van Schayk
Author(s): 
Meredith L. McMorrow, M. Irene Masanja, Elizeus Kahigwa, Salim M. K. Abdulla, AND S. Patrick Kachur
Reference: 
Am J Trop Med Hyg 2010;82 151-155

We evaluated sensitivity and specificity of RDTs during routine use for malaria case management in peripheral health facilities.

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