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Scientific Articles

Parasitology: Imported malaria in children: incidence and risk factors for severity

January 21, 2010 - 07:52 -- Kabogo Ndegwa
Author(s): 
François Dubosa, Alice Dauriaca, Loubna El Mansoufa, Claude Couroublec, Marie Aurela, Alain Martinota
Reference: 
Diagnostic Microbiology and Infectious Disease, Volume 66, Issue 2, February 2010, Pages 169-174

To assess the incidence of imported malaria in children and to determine the frequency of delayed diagnosis and risk factors for severe malaria, we performed a retrospective multicenter cohort study in the northern region of France and included all children with a positive test for malaria from 2000 to 2006.

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Parasitology: Evaluation of rapid diagnostic tests for malaria case management in Gabon

January 21, 2010 - 07:50 -- Kabogo Ndegwa
Author(s): 
Denise Patricia Mawili-Mboumba, Marielle Karine Bouyou Akoteta, Edgard Brice Ngoungoua and Maryvonne Kombila
Reference: 
Diagnostic Microbiology and Infectious Disease, Volume 66, Issue 2, February 2010, Pages 162-168

These tests should be considered as a good alternative to microscopy, allowing not only an efficient and rapid diagnosis of malaria in primary health facilities but also to aid in promoting changes for antimalarial prescription behavior.

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Analgesic and antimalarial activities of crude leaf extract and fractions of Acalypha wilkensiana

January 21, 2010 - 07:46 -- Kabogo Ndegwa
Author(s): 
John A. Udobanga, Paul A. Nwafora and Jude E. Okokon
Reference: 
Journal of Ethnopharmacology Volume 127, Issue 2, 3 February 2010, Pages 373-378

Antiplasmodial and analgesic activities of leaf extract and fractions of Acalypha wilkensiana were evaluated to ascertain the folkloric claim of its antimalarial and analgesic activities.

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A bicomponent Plasmodium falciparum investigational vaccine composed of protein-peptide conjugates

January 20, 2010 - 09:42 -- Ingeborg van Schayk
Author(s): 
Joanna Kubler-Kielb, Fathy Majadly, Zuzana Biesova, Christopher P. Mocca, Chunyan Guo, Ruth Nussenzweig, Victor Nussenzweig, Satish Mishra, Yimin Wu, Louis H. Miller, Jerry M. Keith, Teh-Yung Liu, John B. Robbins, and Rachel Schneerson
Reference: 
PNAS January 19, 2010 vol. 107 no. 3 1172-1177

To provide a CSP-based candidate vaccine, we investigated recombinant CSP and NANP conjugates of various peptide lengths, with different N-terminal amino acids, bound at different ratios to various carrier proteins.

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Open Access | Factors affecting fungus-induced larval mortality in Anopheles gambiae and Anopheles stephensi

January 20, 2010 - 09:29 -- Ingeborg van Schayk
Author(s): 
Tullu Bukhari, Anthonieke Middelman, Constantianus JM Koenraadt, Willem Takken, Bart GJ Knols
Reference: 
Malaria Journal 2010, 9:22 (19 January 2010)

Further data on an interesting new approach for biological mosquito larval control.

Open Access | The Relationship between Anti-merozoite Antibodies and Incidence of Plasmodium falciparum Malaria: A Systematic Review and Meta-analysis

January 19, 2010 - 19:56 -- Ingeborg van Schayk
Author(s): 
Freya J. I. Fowkes, Jack S. Richards, Julie A. Simpson, James G. Beeson
Reference: 
PLoS Med 7(1): e1000218

A systematic review and meta-analysis examining the association between anti-merozoite antibody responses and incidence of Plasmodium falciparum malaria by Freya Fowkes and colleagues aids identification of antigens that confer protection from malaria.

Open Access | Policy forum: The Global Health System: Linking Knowledge with Action—Learning from Malaria

January 19, 2010 - 19:51 -- Ingeborg van Schayk
Author(s): 
Gerald T. Keusch, Wen L. Kilama, Suerie Moon, Nicole A. Szlezák, Catherine M. Michaud
Reference: 
PLoS Med 7(1): e1000179

In the third in a series of articles on the changing nature of global health institutions, Gerald Keusch and colleagues examine institutional arrangements for malaria research

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Open access | Assessing functional annotation transfers with inter-species conserved coexpression: application to Plasmodium falciparum

January 19, 2010 - 19:40 -- Ingeborg van Schayk
Author(s): 
Brehelin L, Florent I, Gascuel O, Marechal E
Reference: 
BMC Genomics 2010, 11:35 (15 January 2010)

We propose a new method that uses gene expression data to assess inter-species annotation transfers.

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Short report: Malarial retinopathy in northern Nigerian children

January 19, 2010 - 19:31 -- Ingeborg van Schayk
Author(s): 
I Mohammed, U Y Ibrahim, M Mukhtar, Z Farouq, P N Obiagwu, and A H Yashua
Reference: 
Trop Doct 2010;40 50-52

Direct ophthalmoscopy seemed to be effective in detecting malarial retinopathy, but only when performed by experienced personnel.

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