Andrew Read and colleagues have proposed that insecticides acting late in the vector lifetime are less susceptible to evolutionary pressures, thereby avoiding insecticide resistance.
This study examines the responses of heat shock protein transcripts, Hsp70 and Hsp90, to dehydration stress in three mosquito species, Aedes aegypti, Anopheles gambiae and Culex pipiens.
No abstract available
These data provide, for the first time, evidence for improved management of children by use of paediatric formulations, and support the further development and use of paediatric ACTs.
There is a strong association between thrombocytopenia and outcome in malaria, suggesting a role for platelets in the pathogenesis of malaria.
This is the first description of close-range mating interactions in incipient An. gambiae species.
Anopheles gambiae, a major vector of malaria, is a complex of cryptic species and subspecies. A new study describes a remarkable behaviour that might contribute to sexual isolation in this species complex: males and females are much more likely to show harmonic convergence of wing beat sounds when courting individuals of the same type.
Overall, these results demonstrate that chronic avian malaria infections, far from being benign, can have significant effects on host fitness and may thus constitute an important selection pressure in wild bird populations.
In this study, we have characterized 25 antigens as a vaccine candidate and screened the potential T-lymphocyte epitopes presented by human leukocyte antigen (HLA)-A, -B, and -DR molecules based on the proteomic data of Plasmodium falciparum.
A study in mice suggests that CSP-based protein-peptide conjugates could be useful vaccines against malaria infection. Further details on the research, next steps and licensing status are discussed in the article.