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Scientific Articles

Open Access | Case report: Congenital Plasmodium vivax malaria mimicking neonatal sepsis: a case report

March 7, 2010 - 12:34 -- Ingeborg van Schayk
Author(s): 
Veronica Del Punta, Maurizio Gulletta, Alberto Matteelli, Vania Spinoni, Antonio Regazzoli, Francesco Castelli
Reference: 
Malaria Journal 2010, 9:63 (1 March 2010)

Although malaria in pregnancy can cause very significant neonatal morbidity, congenital malaria is a very rare condition in both endemic and non-endemic areas.

Open Access | Anopheles gambiae: historical population decline associated with regional distribution of insecticide-treated bed nets in western Nyanza Province, Kenya

March 7, 2010 - 10:05 -- Ingeborg van Schayk
Author(s): 
M Nabie Bayoh, Derrick K Mathias, Maurice R Odiere, Francis M Mutuku, Luna Kamau, John E Gimnig, John M Vulule, William A Hawley, Mary J Hamel, Edward D Walker
Reference: 
Malaria Journal 2010, 9:62 (26 February 2010)

A marked decline of the A. gambiae s.s. population occurred as household ownership of bed nets rose in a region of western Kenya over a 10 year period.

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Impact of Anti-DDT Campaigns on Malaria Control

March 7, 2010 - 09:54 -- Ingeborg van Schayk
Author(s): 
Roberts, Donald R.
Reference: 
Outlooks on Pest Management, Volume 21, Number 1, February 2010 , pp. 4-11(8)

Anti-DDT propaganda typically claimed that insecticide caused all manner of harm to human health. Readily embraced and trumpeted by the popular press, the claims, in reality, never satisfied even the most minimal cause-effect criteria. These criteria are discussed in depth.

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Open Access | Factors influencing implementation of the Ministry of Health-led private medicine retailer programmes on malaria in Kenya

March 7, 2010 - 09:42 -- Ingeborg van Schayk
Author(s): 
Rowa Y, Abuya TO, Mutemi WK, Ochola S, Molyneux C, Marsh V
Reference: 
BMC Public Health 2010, 10:93 (24 February 2010)

This study explored stakeholders' perceptions of the role of private medicine retailers (PMRs), the value and feasibility of programme goals, perceived programme impact, factors influencing implementation and recommendations in three districts of Kenya.

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Open Access | Understanding Human-Plasmodium falciparum Immune Interactions Uncovers the Immunological Role of Worms

March 5, 2010 - 16:45 -- Ingeborg van Schayk
Author(s): 
Christian Roussilhon, Philippe Brasseur, Patrice Agnamey, Jean-Louis Pérignon, Pierre Druilhe
Reference: 
PLoS ONE 5(2): e9309

We investigated here the hypothesis that the delayed acquisition of immunity to malaria could be related to a worm-induced Th2 drive on antimalarial immune responses.

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Open Access | Population Hemoglobin Mean and Anemia Prevalence in Papua New Guinea: New Metrics for Defining Malaria Endemicity?

March 5, 2010 - 16:29 -- Ingeborg van Schayk
Author(s): 
Nicolas Senn, Seri Maraga, Albert Sie, Stephen J. Rogerson, John C. Reeder, Peter Siba, Ivo Mueller
Reference: 
PLoS ONE 5(2): e9375

The aim of this study is to compare population hemoglobin mean and anemia prevalence to established indicators of malaria endemicity, including parasite rates, rates of enlarged spleens in children, and records of (presumptive) malaria diagnosis among populations living with different levels of malaria transmission.

Open Access | High Resolution Niche Models of Malaria Vectors in Northern Tanzania: A New Capacity to Predict Malaria Risk?

March 5, 2010 - 16:06 -- Ingeborg van Schayk
Author(s): 
Manisha A. Kulkarni, Rachelle E. Desrochers, Jeremy T. Kerr
Reference: 
PLoS ONE 5(2): e9396

The interaction between mosquito niche space and microclimate along elevational gradients indicates worrisome potential for climate and land use changes to exacerbate malaria resurgence in the east African highlands. Nevertheless, it is possible to direct interventions precisely to ameliorate potential impacts.

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The blood parasite Haemoproteus reduces survival in a wild bird: a medication experiment

March 5, 2010 - 14:56 -- Ingeborg van Schayk
Author(s): 
Josué Martínez-de la Puente1,*, Santiago Merino1, Gustavo Tomás1,2, Juan Moreno1, Judith Morales, Elisa Lobato, Sonia García-Fraile and Eduardo Jorge Belda
Reference: 
Biology Letters, Published online before print February 24, 2010

In this study we test for the effect of the antimalarial-drug primaquine on the survival probability of wild birds infected by the malaria-like parasite Haemoproteus.

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Mapping of Char10, a novel malaria susceptibility locus on mouse chromosome 9

March 5, 2010 - 12:15 -- Kabogo Ndegwa
Author(s): 
G Min-Oo, A Willemetz, M Tam, F Canonne-Hergaux, M M Stevenson and P Gros
Reference: 
Genes and Immunity, Volume 11, Issue 2 (March 2010) Pages 113-123

We identified a third AcB strain, AcB62 that also carries the PklrI90N mutation. However, AcB62 mice were susceptible to P.chabaudi infection and showed high levels of parasite replication (54–62% peak parasitemia).

Phase 1 safety and immunogenicity trial of the Plasmodium falciparum blood-stage malaria vaccine AMA1-C1/ISA 720 in Australian adults

March 5, 2010 - 12:12 -- Kabogo Ndegwa
Author(s): 
Mark A. Pierce, Ruth D. Ellis, Louis H. Miller et al.
Reference: 
Vaccine, Volume 28, Issue 10, 2 March 2010, Pages 2236-2242

A Phase 1 trial was conducted in malaria-naïve adults to evaluate the recombinant protein vaccine apical membrane antigen 1-Combination 1 (AMA1-C1) formulated in Montanide® ISA 720 (SEPPIC, France), a water-in-oil adjuvant. 

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