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Scientific Articles

Veterinary Medicine-Invited review: Laboratory diagnosis of malaria in nonhuman primates

March 11, 2010 - 13:40 -- Patrick Sampao
Author(s): 
Mehrdad Ameri
Reference: 
Veterinary Clinical Pathology,Volume 39, Issue 1, March 2010, Pages: 5-19

Nonhuman primates (NHPs) are commonly used for biomedical research because of the high level of gene homology that underlies physiologic similarity to human beings. This review focuses on the available laboratory diagnostic tools for malaria in NHPs.

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Clinical Microbiology: Alternatives for Malaria Prophylaxis During the First Trimester of Pregnancy: Our Personal View

March 11, 2010 - 13:31 -- Patrick Sampao
Author(s): 
Urban Hellgren, Lars Rombo
Reference: 
Journal of Travel Medicine,Volume 17, Issue 2, March/April 2010, Pages: 130-132

No abstract available

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Microbiology and virology: Phosphothioate oligodeoxynucleotides inhibit Plasmodium sporozoite gliding motility

March 11, 2010 - 13:21 -- Patrick Sampao
Author(s): 
Peter Liehl, Ana Rita França, Miguel Prudêncio, Eicke Latz, Anna Zaidman-Rémy, Maria M. Mota
Reference: 
Cellular Microbiology,Volume 12, Issue 4, April 2010, Pages: 506-515

Altogether, PS-ODNs might represent a new class of prophylactic anti-malaria agents, which hamper hepatocyte entry by Plasmodium sporozoites.

Immunology: Parasitaemia levels in Plasmodium chabaudi infected-mice modify IFN-gamma and IL-10 expression after a homologous or heterologous challenge

March 11, 2010 - 13:18 -- Patrick Sampao
Author(s): 
M. Aguilar-Medina, R. Ramos-Payan, E. Arambula-Meraz, L. Sanchez-Torres, L. Favila-Castillo.
Reference: 
Parasite Immunology,Volume 32, Issue 4, April 2010, Pages: 267-274

CB6F1 mice infected with the nonlethal Plasmodium chabaudi chabaudi AS suffer parasitaemia levels up to 40% (full parasitaemia, FP) and develop both homologous and heterologous (against the lethal Plasmodium yoelii 17XL) protective immunity.

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Immunology: Boosting antibody responses to Plasmodium falciparum merozoite antigens in children with highly seasonal exposure to infection

March 11, 2010 - 13:14 -- Patrick Sampao
Author(s): 
O. J. Akpogheneta, S. Dunyo, M. Pinder, D. J. Conway
Reference: 
Parasite Immunology,Volume 32, Issue 4, April 2010, Pages: 296-304

Longitudinal cohort studies are important to describe the dynamics of naturally acquired antibody response profiles to defined Plasmodium falciparum malaria antigens relative to clinical malaria episodes.

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Clinical Microbiology: Long-lasting insecticide–treated net usage in eastern Sierra Leone – the success of free distribution

March 11, 2010 - 13:08 -- Patrick Sampao
Author(s): 
Sibylle Gerstl, Sophie Dunkley, Ahmed Mukhtar, Peter Maes, Martin De Smet, Samuel Baker, Jacob Maikere
Reference: 
Tropical Medicine & International Health,Volume 15, Issue 4,April 2010, Pages: 480-488

Our results show that MSF achieved good usage with freely distributed LLINs. It is one of the few areas where results almost achieve the new targets set in 2005 by Roll Back Malaria to have at least 80% of pregnant women and children under 5 years using LLINs by 2010.

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Clinical Microbiology: The effect of food consumption on lumefantrine bioavailability in African children receiving artemether–lumefantrine crushed or dispersible tablets (Coartem®) for acute uncomplicated Plasmodium falciparum malaria

March 11, 2010 - 13:02 -- Patrick Sampao
Author(s): 
Steffen Borrmann, William M. Sallas, Steven E. Kern et al.
Reference: 
Tropical Medicine & International Health,Volume 15, Issue 4, April 2010

Concomitant food consumption may affect absorption of lumefantrine but data in the most important target population, i.e. children, are lacking. Therefore, we evaluated the effect of food intake on oral lumefantrine bioavailability in African children with malaria.

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Short Communication: Comparative fitness assessment of Anopheles stephensi transgenic lines receptive to site-specific integration

March 11, 2010 - 12:34 -- Patrick Sampao
Author(s): 
D. A. Amenya, M. Bonizzoni, A. T. Isaacs, N. Jasinskiene, H. Chen, O. Marinotti, G. Yan, A. A. James
Reference: 
Insect Molecular Biology, Volume 19, Issue 2,April 2010, Pages: 263-269

Genetically modified mosquitoes that are unable to transmit pathogens offer opportunities for controlling vector-borne diseases such as malaria and dengue.

Genetics and Evolution: Chronic malaria infections increase family inequalities and reduce parental fitness: experimental evidence from a wild bird population

March 11, 2010 - 12:10 -- Patrick Sampao
Author(s): 
S. C. L. Knowles, V. Palinauskas, B. C. Sheldon
Reference: 
Journal of Evolutionary Biology, Volume 30, Issue 2, March 2010, Pages: 258-269

Overall, these results demonstrate that chronic avian malaria infections, far from being benign, can have significant effects on host fitness and may thus constitute an important selection pressure in wild bird populations.

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Open Access | Catestatin, an endogenous Chromogranin A-derived peptide, inhibits in vitro growth of Plasmodium falciparum

March 11, 2010 - 11:32 -- Patrick Sampao
Author(s): 
Aziza Akaddar, Cécile Doderer-Lang, Ermanno Candolfi et al.
Reference: 
Cellular and Molecular Life Sciences, Volume 67, Number 6, March, 2010

We have tested the activities of catestatin and other related peptides on the growth of Plasmodium falciparum in vitro.

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