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Scientific Articles

Open Access | Bayesian Geostatistical Modeling of Malaria Indicator Survey Data in Angola

March 25, 2010 - 15:33 -- Ingeborg van Schayk
Author(s): 
Laura Gosoniu, Andre Mia Veta, Penelope Vounatsou
Reference: 
PLoS ONE 5(3): e9322. doi:10.1371/journal.pone.0009322

The 2006–2007 Angola Malaria Indicator Survey (AMIS) is the first nationally representative household survey in the country assessing coverage of the key malaria control interventions and measuring malaria-related burden among children under 5 years of age.

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Open Access | Anopheles aquasalis Infected by Plasmodium vivax Displays Unique Gene Expression Profiles when Compared to Other Malaria Vectors and Plasmodia

March 25, 2010 - 15:06 -- Ingeborg van Schayk
Author(s): 
Ana C. Bahia, Marina S. Kubota, Antonio J. Tempone, Waleria D. Pinheiro, Wanderli P. Tadei, Nágila F. C. Secundino, Yara M. Traub-Csekö, Paulo F. P. Pimenta
Reference: 
PLoS ONE 5(3): e9795. doi:10.1371/journal.pone.0009795

Taken together, these data provide important new information about this poorly studied American malaria vector by revealing differences between the responses of A. aquasalis to P. vivax infection, in relation to better studied mosquito-Plasmodium pairs.

Protein export marks the early phase of gametocytogenesis of the human malaria parasite plasmodium falciparum

March 25, 2010 - 13:54 -- Ingeborg van Schayk
Author(s): 
Francesco Silvestrini, Edwin Lasonder, Anna Olivieri, Grazia Camarda, Ben van Schaijk, Massimo Sanchez, Sumera Younis Younis, Robert Sauerwein, and Pietro Alano
Reference: 
Mol. Cell. Proteomics. published 22 March 2010, 10.1074/mcp.M900479-MCP200

This work indicates that protein export profoundly marks early sexual differentiation in P. falciparum, probably contributing to host cell remodelling in this phase of the life cycle, and that gametocyte-enriched molecules are recruited to modulate this process in gametocytogenesis.

Predictive factors of severe disease secondary to falciparum malaria among travelers

March 25, 2010 - 13:39 -- Ingeborg van Schayk
Author(s): 
G. Saliba, W. Kamouh, A. Fontanet, J. Le Bras
Reference: 
Pathologie Biologie, In Press, Corrected Proof, Available online 19 March 2010

This study points out two particularly interesting results: severe malaria is significantly associated with the infection by a chloroquine resistant P. falciparum phenotype and with the parasite's acquisition in the south-eastern asian region.

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Short report: Can urine dipstick tests detect renal impairment in Plasmodium falciparum malaria in a rural setup?

March 25, 2010 - 12:50 -- Ingeborg van Schayk
Author(s): 
Sudhanshu S Pati and Saroj K Mishra
Reference: 
Trop Doct 2010;40 106-107

The detection of haematuria using a dipstick seems to be a highly specific and sensitive method of observing renal impairment in malaria. This is probably the first study which utilizes a commonly available tool that can be easily adopted for early recognition in rural areas.

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Short report: Rhabdomyolysis in falciparum malaria - a series of twelve cases (five children and seven adults)

March 25, 2010 - 12:42 -- Ingeborg van Schayk
Author(s): 
Saroj K Mishra, Sudhanshu S Pati, Kishore C Mahanta, and Sanjib Mohanty
Reference: 
Trop Doct 2010;40 87-88

We report on 12 patients with evidence of skeletal muscle injury in severe malaria from Rourkela, Orissa State, India.

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Open Access | Plasmodium falciparum transcriptional CDK-related kinase with a crucial role in parasite proliferation associates with histone deacetylase activity

March 25, 2010 - 12:27 -- Ingeborg van Schayk
Author(s): 
Jean Halbert, Lawrence Ayong, Leila Equinet, Karine Le Roch, Mary Hardy, Dean Goldring, Luc Reininger, Norman Waters, Debopam Chakrabarti, and Christian Doerig
Reference: 
Eukaryot. Cell. published 19 March 2010, 10.1128/EC.00005-10

Here, we report the characterisation of Pfcrk-3 (P. falciparum CDK-related kinase 3, PlasmoDB identifier PFD0740w), an unusually large CDK-related protein whose kinase domain displays maximal homology to those CDKs which are, in other eukaryotes, involved in the control of transcription.

Open Access | Anopheles (Nyssorhynchus) atacamensis (Diptera: Culicidae), a new species from Northern Chile

March 24, 2010 - 11:12 -- Ingeborg van Schayk
Author(s): 
González, Christian R; Sallum, Maria Anice Mureb
Reference: 
Mem. Inst. Oswaldo Cruz [online]. 2010, vol.105, n.1, pp. 13-24

Anopheles (Nyssorhynchus) atacamensis, a new species in the subgenus Nyssorhynchus, is described and validated using morphological characters of the male and female adult, male genitalia and immature stages.

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Open Access | Quinine-Resistant Malaria in Traveler Returning from Senegal, 2007

March 24, 2010 - 11:05 -- Ingeborg van Schayk
Author(s): 
B. Pradines et al.
Reference: 
EID, Volume 16, Number 3–March 2010

We describe clinical and parasitologic features of in vivo and in vitro Plasmodium falciparum resistance to quinine in a nonimmune traveler who returned to France from Senegal in 2007 with severe imported malaria. 

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Open Access | Serologic Markers for Detecting Malaria in Areas of Low Endemicity, Somalia, 2008

March 24, 2010 - 10:41 -- Ingeborg van Schayk
Author(s): 
T. Bousema et al.
Reference: 
EID, Volume 16, Number 3–March 2010

Areas in which malaria is not highly endemic are suitable for malaria elimination, but assessing transmission is difficult because of lack of sensitivity of commonly used methods. We evaluated serologic markers for detecting variation in malaria exposure in Somalia.

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