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Scientific Articles

Access to malaria treatment in young children of rural Burkina Faso

November 26, 2009 - 12:55 -- Ingeborg van Schayk
Author(s): 
Maike Tipke, Valerie R Louis, Maurice Ye, Manuela De Allegri, Claudia Beiersmann, Ali Sie, Olaf Mueller, Albrecht Jahn
Reference: 
Malaria Journal 2009, 8:266 (24 November 2009)

This deals with a subject of great relevance for malaria control in Africa, the need to increase access to anti-malarial treatment through community health works and home-treatment.

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Cost-effectiveness analysis of rapid diagnostic test, microscopy and syndromic approach in the diagnosis of malaria in Nigeria: implications for scaling-up deployment of ACT

November 26, 2009 - 12:49 -- Ingeborg van Schayk
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Author(s): 
Benjamin SC Uzochukwu, Eric N Obikeze, Obinna E Onwujekwe, Chima A Onoka, Ulla K Griffiths
Reference: 
Malaria Journal 2009, 8:265 (23 November 2009)

Paper comparing different diagnostic methods used in Nigeria, from a cost-effectiveness view point .

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Factors associated with use and non-use of mosquito nets owned in Oromia and Amhara Regional States, Ethiopia

November 26, 2009 - 12:44 -- Ingeborg van Schayk
Author(s): 
Carol A Baume, Richard Reithinger, Sara Woldehanna
Reference: 
Malaria Journal 2009, 8:264 (23 November 2009)

The authors present important and original in-depth information on the reasons for use and non-use of ITNs. Such information is timely and of relevance to malaria control programmes throughout the region.

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Cellular response to modified Plasmodium falciparum MSP119 antigens in individuals previously exposed to natural malaria infection

November 26, 2009 - 12:39 -- Ingeborg van Schayk
Author(s): 
Christian MF Okafor, Chiaka I Anumudu, Yusuf O Omosun, Chairat Uthaipibull, Idowu Ayede, Henrietta O Awobode, Alex B Odaibo, Jean Langhorne, Anthony A Holder, Roseangela I Nwuba, Marita Troye-Blomberg
Reference: 
Malaria Journal 2009, 8:263 (23 November 2009)

This preliminary study suggests that this specific mutant MSP119 27+31+34+43, which also abrogates the binding of all known blocking monoclonal antibodies without affecting the processing-inhibitory antibody epitope, might be a better choice for an MSP1-based malaria vaccine.

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Test characteristics of the SD FK80 Plasmodium falciparum/Plasmodium vivax malaria rapid diagnostic test in a non-endemic setting

November 26, 2009 - 12:29 -- Ingeborg van Schayk
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Author(s): 
Philippe Gillet, David PJ van Dijk, Emmanuel Bottieau, Lieselotte Cnops, Marjan Van Esbroeck, Jan Jacobs
Reference: 
Malaria Journal 2009, 8:262 (22 November 2009)

The SD FK80 P.f/P.v Malaria Antigen Rapid Test (Standard Diagnostics, Korea) (FK80) is a three-band malaria rapid diagnostic test detecting Plasmodium falciparum histidine-rich protein-2 (HRP-2) and Plasmodium vivax-specific lactate dehydrogenase (Pv-pLDH). The present study assessed its performance in a non-endemic setting.

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Erythropoietin and its receptors in the brainstem of adults with fatal falciparum malaria

November 26, 2009 - 12:21 -- Ingeborg van Schayk
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Author(s): 
Isabelle M Medana, Nicholas PJ Day, Tran Tinh Hien, Nicholas J White, Gareth DH Turner
Reference: 
Malaria Journal 2009, 8:261 (22 November 2009)

Whether different endogenous protein expression levels of Epo or differences in the abundance of its receptor components could account for the extent of structural neuropathological changes or neurological complications in adults with severe malaria was investigated.

Improving childhood malaria treatment and referral practices by training patent medicine vendors in rural south-east Nigeria

November 26, 2009 - 12:15 -- Ingeborg van Schayk
Author(s): 
Theodora A Okeke, Benjamin SC Uzochukwu
Reference: 
Malaria Journal 2009, 8:260 (20 November 2009)

This study aimed to determine the feasibility and impact of training rural drug vendors on community-based malaria treatment and advice with referral of severe cases to a health facility.

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Population structure analyses and demographic history of the malaria vector Anopheles albimanus from the Caribbean and the Pacific regions of Colombia

November 26, 2009 - 12:10 -- Ingeborg van Schayk
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Author(s): 
Lina A Gutierrez, Nelson J Naranjo, Astrid V Cienfuegos, Carlos E Muskus, Shirley Luckhart, Jan E Conn, Margarita M Correa
Reference: 
Malaria Journal 2009, 8:259 (19 November 2009)

This study was conducted to estimate intra-population genetic diversity, genetic differentiation and demographic history of An. albimanus populations because knowledge of vector population structure is a useful tool to guide malaria control programmes.

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The relationship of Plasmodium falciparum humeral immunity with HIV-1 immunosuppression and treatment efficacy in Zambia

November 26, 2009 - 11:57 -- Ingeborg van Schayk
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Author(s): 
Jean-Pierre Van geertruyden, Erika Van Eijk, Francisca Yosaatmadja, Webster Kasongo, Modest Mulenga, Umberto D'Alessandro, Stephen Rogerson
Reference: 
Malaria Journal 2009, 8:258 (18 November 2009)

This study reports the impact of HIV-1 infection and other variables on the level of malaria humoral immunity in adults with clinical malaria and whether humoral immune suppression was a risk factor for treatment failure.

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Self-reported data: a major tool to assess compliance with anti-malarial combination therapy among children in Senegal

November 26, 2009 - 11:48 -- Ingeborg van Schayk
Author(s): 
Aurelia Souares, Patricia Moulin, Sophie Sarrassat, Marie-Paule Carlotti, Richard Lalou, Jean-Yves Le Hesran
Reference: 
Malaria Journal 2009, 8:257 (17 November 2009)

Different techniques used to measure compliance were compared among children treated by the anti-malarial amodiaquine/sulphadoxine-pyrimethamine (AQ/SP) combination therapy, in use in Senegal between 2004 and 2006.

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