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Scientific Articles

Open Access | Plasmodium falciparum var gene expression is modified by host immunity

December 24, 2009 - 14:25 -- Ingeborg van Schayk
Author(s): 
George M. Warimwe, Thomas M. Keane, Gregory Fegan, Jennifer N. Musyoki, Charles R. J. C. Newton, Arnab Pain, Matthew Berriman, Kevin Marsh, and Peter C. Bull
Reference: 
PNAS December 22, 2009 vol. 106 no. 51 21801-21806

Here, in a study of 217 Kenyan children with malaria, we show that expression of a group of var genes “cys2,” containing a distinct pattern of cysteine residues, is associated with low host immunity.

Open Access : Using high spatial resolution remote sensing for risk mapping of malaria occurrence in the Nouna district, Burkina Faso

December 24, 2009 - 14:14 -- Ingeborg van Schayk
Author(s): 
Peter Dambach1*, Ali Sie´ 2, Jean-Pierre Lacaux3,4, Ce´ cile Vignolles4, Vanessa Machault4,5 and Rainer Sauerborn6,1
Reference: 
Global Health Action 2009

Potential high and low risks for malaria at the village level can be differentiated from satellite data.

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Open Access | Local scale prediction of Plasmodium falciparum malaria transmission in an endemic region using temperature and rainfall

December 24, 2009 - 14:07 -- Ingeborg van Schayk
Author(s): 
Yazoume´ Ye´ 1*, Moshe Hoshen2, Catherine Kyobutungi1, Vale´ rie R. Louis3 and Rainer Sauerborn4,3
Reference: 
Global Health Action 2009

We develop, fit and validate a non-spatial dynamic model driven by meteorological conditions that can capture seasonal malaria transmission dynamics at the village level in a malaria holoendemic area of north-western Burkina Faso.

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Open Access | Decreasing childhood mortality and increasing proportion of malaria deaths in rural Burkina Faso

December 24, 2009 - 14:00 -- Ingeborg van Schayk
Author(s): 
Heribert Ramroth1*§, Robert P. Ndugwa1§, Olaf Mu¨ ller1, Yazoume Ye´ 2, Ali Sie´ 3, Bocar Kouyate´ 4 and Heiko Becher1
Reference: 
Global Health Action 2009

The aim of this study was to describe temporal trends for malaria and all-cause mortality by combining a series of clinical and intervention studies conducted in Burkina Faso.

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Open Access | Knowledge, attitudes and practice about malaria in rural Tigray, Ethiopia

December 24, 2009 - 13:55 -- Ingeborg van Schayk
Author(s): 
Johan Paulander1, Henrik Olsson1, Hailemariam Lemma2, Asefaw Getachew2 and Miguel San Sebastian3
Reference: 
Global Health Action 2009

To assess the knowledge, attitude and practice (KAP) regarding malaria and their determinants in
a rural population of northern Ethiopia.

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Open Access | The World Malaria Report 2009

December 24, 2009 - 13:48 -- Ingeborg van Schayk
Author(s): 
World Health Organization
Reference: 
WHO publications

Half of the world's population is at risk of malaria, and an estimated 247 million cases led to nearly 881 000 deaths in 2006. The World malaria report 2008 describes the global distribution of cases and deaths, how WHO-recommended control strategies have been adopted and implemented in endemic countries, sources of funding for malaria control, and recent evidence that prevention and treatment can alleviate the burden of disease. 

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Sugar Deprivation Reduces Insemination of Anopheles gambiae (Diptera: Culicidae), Despite Daily Recruitment of Adults, and Predicts Decline in Model Populations

December 24, 2009 - 13:40 -- Ingeborg van Schayk
Author(s): 
Stone, C. M.; Taylor, R. M.; Roitberg, B. D.; Foster, W. A.
Reference: 
Journal of Medical Entomology, Volume 46, Number 6, November 2009 , pp. 1327-1337(11)

Our research tests the hypothesis that the inability to sugar-feed reduces the insemination rate in mosquito populations.

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Open Access | Discovery of Plasmodium modulators by genome-wide analysis of circulating hemocytes in Anopheles gambiae

December 24, 2009 - 13:25 -- Ingeborg van Schayk
Author(s): 
Sofia B. Pinto, Fabrizio Lombardo, Anastasios C. Koutsos, Robert M. Waterhouse, Krista McKay, Chunju An, Chandra Ramakrishnan, Fotis C. Kafatos, and Kristin Michel
Reference: 
PNAS December 15, 2009 vol. 106 no. 50 21270-21275

We assess, via an RNAi screen, the roles in development of Plasmodium berghei of 63 genes expressed in hemocytes and provide a molecular comparison of the transcriptome of these cells during malaria infection.

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Open Access | Substantial Contribution of Submicroscopical Plasmodium falciparum Gametocyte Carriage to the Infectious Reservoir in an Area of Seasonal Transmission

December 24, 2009 - 13:05 -- Ingeborg van Schayk
Author(s): 
Ouédraogo AL, Bousema T, Schneider P, de Vlas SJ, Ilboudo-Sanogo E, et al.
Reference: 
PLoS ONE 4(12): e8410

Submicroscopical gametocyte carriage is common in an area of seasonal transmission in Burkina Faso and contributes substantially to the human infectious reservoir.

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