Both AL and DP were safe and well tolerated for the treatment of uncomplicated malaria in young HIV-infected and uninfected children.
This study confirms the prozone effect as a cause of false-negative HRP-2 RDTs in samples with hyperparasitaemia.
The study aimed to assess the impact of chemoresistance on mortality attributable to malaria in a rural area of Senegal.
Dihydroartemisinin-piperaquine (DHA-PQP) is a promising fixed-dose ACT with limited information on its safety and efficacy in African children.
This study provides data on malaria vector species composition and insecticide susceptibility status from three localities in Guinea Conakry.
Three insecticides – the pyrethroid deltamethrin, the carbamate carbosulfan and the organophosphate chlorpyrifos-methyl – were tested on mosquito nets in experimental huts to determine their potential for introduction as malaria control measures.
We have analyzed the in vitro chemosensitivity profiles of 115 Kenyan isolates for chloroquine (CQ), piperaquine, lumefantrine (LM), and dihydroartemisinin in association with polymorphisms in pfcrt at codon 76 and pfmdr1 at codon 86, as well as with variations of the copy number of pfmdr1.
To study the origin and evolution of pyrimethamine resistance on the Indian subcontinent, microsatellite markers flanking the pfdhfr gene were mapped.
Hemoglobin (Hb) degradation is essential for the growth of the intraerythrocytic stages of malarial parasites.
Antigen-specific antibodies (Abs) to the 19-kDa carboxy-terminal region of Plasmodium falciparum merozoite surface protein 1 (MSP119) play an important role in protective immunity to malaria.