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Scientific Articles

Loop-Mediated Isothermal Amplification (LAMP) for Rapid Identification of Anopheles gambiae and Anopheles arabiensis Mosquitoes

December 18, 2009 - 16:41 -- Ingeborg van Schayk
Author(s): 
Mariangela Bonizzoni, Yaw Afrane, AND Guiyun Yan
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Am J Trop Med Hyg 2009;81 1030-1034

The LAMP-based species identification method can be performed in a water bath and completed within 65 minutes, representing an alternative method for rapid and field applicable vector species diagnosis.

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Beyond Nature and Nurture: Phenotypic Plasticity in Blood-Feeding Behavior of Anopheles gambiae s.s. When Humans Are Not Readily Accessible

December 18, 2009 - 16:38 -- Ingeborg van Schayk
Author(s): 
Thierry Lefèvre, Louis-Clément Gouagna, Kounbrobr Roch Dabiré, Eric Elguero, Didier Fontenille, François Renaud, Carlo Costantini, AND Frédéric Thomas
Reference: 
Am J Trop Med Hyg 2009;81 1023-1029

This paradox can be interpreted as the evolution of a plastic strategy of feeding behavior in this field population of An. gambiae because of the greater accessibility of readily available, although less-preferred, hosts.

Short report: Natural Hybrid between Anopheles kleini and Anopheles sinensis

December 18, 2009 - 16:33 -- Ingeborg van Schayk
Author(s): 
Deepak Joshi, Wej Choochote, AND Gi-Sik Min
Reference: 
Am J Trop Med Hyg 2009;81 1020-1022

While analyzing wild mosquitoes caught in Paju, South Korea, we identified one egg-laying hybrid female between Anopheles kleini and Anopheles sinensis.

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Towards a Genetic Map for Anopheles albimanus: Identification of Microsatellite Markers and a Preliminary Linkage Map for Chromosome 2

December 18, 2009 - 16:30 -- Ingeborg van Schayk
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Author(s): 
R. Patricia Penilla, Hilary Ranson, Norma Padilla, John C. Morgan, Keith Steen, Patricia Pignatelli, Américo D. Rodríguez, Janet Hemingway, William G. Brogdon, William C. Black, IV, AND Mark Q. Benedict
Reference: 
Am J Trop Med Hyg 2009;81 1007-1012

This study significantly increases the number of genetic markers available for An. albimanus and provides useful tools for population genetics and genetic mapping studies in this important malaria vector.

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High Levels of Plasmodium falciparum Rosetting in All Clinical Forms of Severe Malaria in African Children

December 18, 2009 - 16:23 -- Ingeborg van Schayk
Author(s): 
Ogobara K. Doumbo, Mahamadou A. Thera, Abdoulaye K. Koné, Ahmed Raza, Louisa J. Tempest, Kirsten E. Lyke, Christopher V. Plowe, AND J. Alexandra Rowe
Reference: 
Am J Trop Med Hyg 2009;81 987-993

We investigated the relationship between rosetting and clinical malaria in 209 Malian children enrolled in a case-control study of severe malaria.

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Therapeutic Efficacy and Effects of Artesunate-Mefloquine and Mefloquine Alone on Malaria-Associated Anemia in Children with Uncomplicated Plasmodium falciparum Malaria in Southwest Nigeria

December 18, 2009 - 16:19 -- Ingeborg van Schayk
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Author(s): 
Akintunde Sowunmi, Grace O. Gbotosho, Christian Happi, Titilope Okuboyejo, Onikepe Folarin, Sulayman Balogun, AND Obaro Michael
Reference: 
Am J Trop Med Hyg 2009;81 979-986

Both regimens were well tolerated. AMQ clears parasitemia and reduces gametocyte carriage more rapidly and causes lesser fall in hematocrit than MQ, but both regimens are effective treatment of uncomplicated P. falciparum malaria in Nigerian children.

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Chlorproguanil–Dapsone–Artesunate versus Chlorproguanil–Dapsone: A Randomized, Double-Blind, Phase III Trial in African Children, Adolescents, and Adults with Uncomplicated Plasmodium falciparum Malaria

December 18, 2009 - 16:14 -- Ingeborg van Schayk
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Author(s): 
Alfred B. Tiono, Alassane Dicko, Dennis A. Ndububa, Tsiri Agbenyega, Simon Pitmang, Jacob Awobusuyi, Allan Pamba, Stephan Duparc, Li-Ean Goh, Emma Harrell, Nick Carter, Stephen A. Ward, Brian Greenwood, AND Peter A. Winstanley
Reference: 
Am J Trop Med Hyg 2009;81 969-978

This multi-center, randomized, parallel-group, double-blind, double-dummy study compared the efficacy and safety of chlorproguanil–dapsone–artesunate (CDA) and chlorproguanil–dapsone (CPG–DDS) in the treatment of falciparum malaria in Africa (Burkina Faso, Ghana, Mali, Nigeria).

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Recurrent Parasitemias and Population Dynamics of Plasmodium vivax Polymorphisms in Rural Amazonia

December 18, 2009 - 15:58 -- Ingeborg van Schayk
Author(s): 
Pamela Orjuela-Sánchez, Natal Santos da Silva, Mônica da Silva-Nunes, AND Marcelo Urbano Ferreira
Reference: 
Am J Trop Med Hyg 2009;81 961-968

Here we describe high rates of P. vivax recurrence (26–40% 180 days after treatment) in two cohorts of rural Amazonians exposed to low levels of malaria transmission after a vivax malaria episode treated with chloroquine-primaquine.

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Plasmodium falciparum and Plasmodium vivax Infections in the Peruvian Amazon: Propagation of Complex, Multiple Allele-Type Infections without Super-Infection

December 18, 2009 - 15:54 -- Ingeborg van Schayk
Author(s): 
Patrick L. Sutton, Victor Neyra, Jean N. Hernandez, AND OraLee H. Branch
Reference: 
Am J Trop Med Hyg 2009;81 950-960

The results suggest propagation of mixed infections by multiple inocula, not super-infection, implying decade-long opportunity for outcrossing in these mixed infections.

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A Temporal-Spatial Analysis of Malaria Transmission in Adama, Ethiopia

December 18, 2009 - 10:37 -- Ingeborg van Schayk
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Author(s): 
Ingrid Peterson, Luisa N. Borrell, Wafaa El-Sadr, AND Awash Teklehaimanot
Reference: 
Am J Trop Med Hyg 2009;81 944-949

Findings support the use of small scale mapping and targeted vector control in urban malaria control programs in Africa.

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