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Scientific Articles

Open Access | The Relationship between Anti-merozoite Antibodies and Incidence of Plasmodium falciparum Malaria: A Systematic Review and Meta-analysis

January 19, 2010 - 19:56 -- Ingeborg van Schayk
Author(s): 
Freya J. I. Fowkes, Jack S. Richards, Julie A. Simpson, James G. Beeson
Reference: 
PLoS Med 7(1): e1000218

A systematic review and meta-analysis examining the association between anti-merozoite antibody responses and incidence of Plasmodium falciparum malaria by Freya Fowkes and colleagues aids identification of antigens that confer protection from malaria.

Open Access | Policy forum: The Global Health System: Linking Knowledge with Action—Learning from Malaria

January 19, 2010 - 19:51 -- Ingeborg van Schayk
Author(s): 
Gerald T. Keusch, Wen L. Kilama, Suerie Moon, Nicole A. Szlezák, Catherine M. Michaud
Reference: 
PLoS Med 7(1): e1000179

In the third in a series of articles on the changing nature of global health institutions, Gerald Keusch and colleagues examine institutional arrangements for malaria research

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Open access | Assessing functional annotation transfers with inter-species conserved coexpression: application to Plasmodium falciparum

January 19, 2010 - 19:40 -- Ingeborg van Schayk
Author(s): 
Brehelin L, Florent I, Gascuel O, Marechal E
Reference: 
BMC Genomics 2010, 11:35 (15 January 2010)

We propose a new method that uses gene expression data to assess inter-species annotation transfers.

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Short report: Malarial retinopathy in northern Nigerian children

January 19, 2010 - 19:31 -- Ingeborg van Schayk
Author(s): 
I Mohammed, U Y Ibrahim, M Mukhtar, Z Farouq, P N Obiagwu, and A H Yashua
Reference: 
Trop Doct 2010;40 50-52

Direct ophthalmoscopy seemed to be effective in detecting malarial retinopathy, but only when performed by experienced personnel.

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Open Access | Evaluation of PermaNet 3.0 a deltamethrin-PBO combination net against Anopheles gambiae and pyrethroid resistant Culex quinquefasciatus mosquitoes: an experimental hut trial in Tanzania

January 19, 2010 - 16:04 -- Ingeborg van Schayk
Author(s): 
Patrick Tungu, Stephen Magesa, Caroline Maxwell, Robert Malima, Dennis Masue, Wema Sudi, Joseph Myamba, Olivier Pigeon, Mark Rowland
Reference: 
Malaria Journal 2010, 9:21 (19 January 2010)

Interesting study that highlights the importance of developing effective control tools that can be utilized in resistance management programmes. Although the results of the paper do not provide overwhelming support for the deltamethrin and piperonyl butoxide combination bednet, it is an important negative result.

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Open Access | Commentary: Plasmodium knowlesi malaria in Vietnam: some clarifications

January 19, 2010 - 15:59 -- Ingeborg van Schayk
Author(s): 
Peter Van den Eede, Indra Vythilingam, Thang Ngo Duc, Hong Nguyen Van, Le Xuan Hung, Umberto D'Alessandro, Annette Erhart
Reference: 
Malaria Journal 2010, 9:20 (18 January 2010)

Response by the authors to a recent commentary published in Malaria Journal.

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Open Access | Gel versus capillary electrophoresis genotyping for categorizing treatment outcomes in two anti-malarial trials in Uganda

January 19, 2010 - 15:54 -- Ingeborg van Schayk
Author(s): 
Vinay Gupta, Grant Dorsey, Alan E Hubbard, Philip J Rosenthal, Bryan Greenhouse
Reference: 
Malaria Journal 2010, 9:19 (15 January 2010)

This paper presents strong evidence that capillary electrophoresis (CE) is better than gel electrophoresis in discriminating recrudescence from reinfection. This has important implications for drug development.

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Open Access | Intermittent screening and treatment versus intermittent preventive treatment of malaria in pregnancy: user acceptability

January 19, 2010 - 15:45 -- Ingeborg van Schayk
Author(s): 
Lucy A Smith, Caroline Jones, Rose O Adjei, Gifty D Antwi, Nana A Afrah, Brian Greenwood, Daniel Chandramohan, Harry Tagbor, Jayne Webster
Reference: 
Malaria Journal 2010, 9:18 (14 January 2010)

Due to very high and increasing resistance of malaria parasites to SP in Africa there is a need for alternative methods to protect pregnant women from the effects of malaria in pregnancy. This study describes pregnant women’s acceptability of such an alternative method based on intermittent RDT screening followed by treatment of those found positive. 

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Open Access | Improved methods for magnetic purification of malaria parasites and haemozoin

January 19, 2010 - 15:40 -- Ingeborg van Schayk
Author(s): 
Charles C Kim, Emily B Wilson, Joseph L DeRisi
Reference: 
Malaria Journal 2010, 9:17 (14 January 2010)

How to construct a cheap separation system for isolating haemozoin and infected red blood cells from malaria infected blood cultures using a magnet. The study is the first report of the effect of magnet strength and configuration on the efficiency of isolation of both haemozoin and iRBCs.

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