In this issue of Blood, Bridges and colleagues report that Plasmodium falciparum–infected erythrocytes are able to attach to the endothelial surface by binding platelet-decorated VWF strands in a CD36-dependent fashion, revealing a new mechanism for erythrocyte cytoadherence in malaria
No abstract available
Jacquerioz FA, Croft AM . Drugs for preventing malaria in travellers. Cochrane Database Syst Rev 2009:CD006491.
In the present study, the use of CDC light traps showed it to be much more abundant than previously found but there was no evidence to suggest it was a malaria vector in this region.
A mathematical model of erythropoiesis subject to malaria infection is developed by combining ideas from previous models that addressed only one of the two phenomena.
Using affinity purification coupled with mass-spectrometric analysis we identify a messenger ribonucleoprotein (mRNP) from Plasmodium berghei gametocytes defined by DOZI and the Sm-like factor CITH (homolog of worm CAR-I and fly Trailer Hitch).
Finally, our data and that of others indicated that chimpanzees and bonobos maintain malaria parasites, to which humans are susceptible, a factor of some relevance to the renewed efforts to eradicate malaria.
This is an important paper which demonstrates the utility of a mass drug treatment approach to malaria control in areas of relatively high transmission in south-western Cambodia.
The relative effectiveness of various drug combinations was compared by a multi-treatment Bayesian random-effect meta-analysis.
Quassia amara L. (Family Simaroubaceae) is known to have several medicinal properties including the activity against malaria. An HPLC method was employed for purification of the biologically active quassinoids; quassin (Q) and neo-quassin (NQ), further characterized by MALDI-TOF analyses.