The world's scientific and social network for malaria professionals

Anne-Marit Sponaas, Ana Paula Freitas do Rosario, Cecile Voisine, Beatris Mastelic, Joanne Thompson, Sandra Koernig, William Jarra, Laurent Renia, Marjorie Mauduit, Alexandre J. Potocnik, and Jean Langhorne

Reference:

Blood, 24 December 2009, Vol. 114, No. 27, pp. 5522-5531.

During Plasmodium chabaudi infection in mice, a population of CD11bhighLy6C+ monocytes are generated in bone marrow, most of which depend on the chemokine receptor CCR2 for migration from bone marrow to the spleen.

Medical Condition:

malaria

monocytes

spleen

Open Access | Plasmodium falciparum var gene expression is modified by host immunity

Author(s):

George M. Warimwe, Thomas M. Keane, Gregory Fegan, Jennifer N. Musyoki, Charles R. J. C. Newton, Arnab Pain, Matthew Berriman, Kevin Marsh, and Peter C. Bull

Reference:

PNAS December 22, 2009 vol. 106 no. 51 21801-21806

Here, in a study of 217 Kenyan children with malaria, we show that expression of a group of var genes “cys2,” containing a distinct pattern of cysteine residues, is associated with low host immunity.

Medical Condition:

Plasmodium falciparum

var gene expression

host immunity

Open Access : Using high spatial resolution remote sensing for risk mapping of malaria occurrence in the Nouna district, Burkina Faso

Author(s):

Peter Dambach1*, Ali Sie´ 2, Jean-Pierre Lacaux3,4, Ce´ cile Vignolles4, Vanessa Machault4,5 and Rainer Sauerborn6,1

Reference:

Global Health Action 2009

Potential high and low risks for malaria at the village level can be differentiated from satellite data.

Technology:

Country:

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Open Access | Local scale prediction of Plasmodium falciparum malaria transmission in an endemic region using temperature and rainfall

Author(s):

Yazoume´ Ye´ 1*, Moshe Hoshen2, Catherine Kyobutungi1, Vale´ rie R. Louis3 and Rainer Sauerborn4,3

Reference:

Global Health Action 2009

We develop, fit and validate a non-spatial dynamic model driven by meteorological conditions that can capture seasonal malaria transmission dynamics at the village level in a malaria holoendemic area of north-western Burkina Faso.

Technology:

modelling

Person:

children

Medical Condition:

malarial

Plasmodium falciparum

Open Access | Decreasing childhood mortality and increasing proportion of malaria deaths in rural Burkina Faso

Author(s):

Heribert Ramroth1*§, Robert P. Ndugwa1§, Olaf Mu¨ ller1, Yazoume Ye´ 2, Ali Sie´ 3, Bocar Kouyate´ 4 and Heiko Becher1

Reference:

Global Health Action 2009

The aim of this study was to describe temporal trends for malaria and all-cause mortality by combining a series of clinical and intervention studies conducted in Burkina Faso.

Person:

Country:

Region:

Medical Condition:

Open Access | Knowledge, attitudes and practice about malaria in rural Tigray, Ethiopia

Author(s):

Johan Paulander1, Henrik Olsson1, Hailemariam Lemma2, Asefaw Getachew2 and Miguel San Sebastian3

Reference:

Global Health Action 2009

To assess the knowledge, attitude and practice (KAP) regarding malaria and their determinants in
a rural population of northern Ethiopia.

Country:

City:

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Open Access | The World Malaria Report 2009

Author(s):

World Health Organization

Reference:

WHO publications

Half of the world's population is at risk of malaria, and an estimated 247 million cases led to nearly 881 000 deaths in 2006. The World malaria report 2008 describes the global distribution of cases and deaths, how WHO-recommended control strategies have been adopted and implemented in endemic countries, sources of funding for malaria control, and recent evidence that prevention and treatment can alleviate the burden of disease.

Organization:

World Health Organization

Medical Condition:

malaria

report