This is the first description of close-range mating interactions in incipient An. gambiae species.
Anopheles gambiae, a major vector of malaria, is a complex of cryptic species and subspecies. A new study describes a remarkable behaviour that might contribute to sexual isolation in this species complex: males and females are much more likely to show harmonic convergence of wing beat sounds when courting individuals of the same type.
Overall, these results demonstrate that chronic avian malaria infections, far from being benign, can have significant effects on host fitness and may thus constitute an important selection pressure in wild bird populations.
In this study, we have characterized 25 antigens as a vaccine candidate and screened the potential T-lymphocyte epitopes presented by human leukocyte antigen (HLA)-A, -B, and -DR molecules based on the proteomic data of Plasmodium falciparum.
A study in mice suggests that CSP-based protein-peptide conjugates could be useful vaccines against malaria infection. Further details on the research, next steps and licensing status are discussed in the article.
The malaria parasite harbours an indispensable plastid known as the ‘apicoplast’. The apicoplast’s exact role remains uncertain, but it houses components involved in fatty acid, isoprenoid and haem biosyntheses.
No abstract available
This study represents the first phase III trial of the safety, tolerability, and effectiveness of tafenoquine for malaria prophylaxis.
A series of acetylenic chalcones were evaluated for antimalarial and antitubercular activity.
Phytochemical investigation of CHCl3 extract of the Gomphostemma niveum leaves led to the isolation of two new diterpene, compound 1 and 2. Their structures were elucidated by spectroscopic procedures and single crystal XRD.