The world's scientific and social network for malaria professionals
Subscribe to free Newsletter | 10372 malaria professionals are enjoying the free benefits of MalariaWorld today

Scientific Articles

A recombinant vaccine based on domain II of Plasmodium vivax Apical Membrane Antigen 1 induces high antibody titres in mice

August 16, 2010 - 14:24 -- Patrick Sampao
Author(s): 
Fernanda G., Daniel Y., et al
Reference: 
Vaccine, Volume 28, Issue 38, 31 August 2010, Pages 6183-6190

These results demonstrate that a recombinant protein containing PvAMA-1 DII is immunogenic when administered in different adjuvant formulations, and indicate that this region of the AMA-1 protein should continue to be evaluated as part of a subunit vaccine against vivax malaria.

Product: 
Medical Treatment: 

Open Access | Malaria risk in Corsica, former hot spot of malaria in France

August 14, 2010 - 13:28 -- Patrick Sampao
Author(s): 
Toty C, Barre H, Le Goff G, Larget-Thiery I, Rahola N, Couret D, Fontenille D
Reference: 
Malaria Journal 2010, 9:231 (12 August 2010)

The prevalence of Plasmodium falciparum and Plasmodium vivax malaria was very high in Corsica just before the Second World War. The last outbreak was in 1972 and the most recent indigenous case was in 2006.

Country: 
Region: 
Medical Condition: 

Open Access | Retinopathy in severe malaria in Ghanaian children - overlap between fundus changes in cerebral and non-cerebral malaria

August 14, 2010 - 13:21 -- Patrick Sampao
Author(s): 
Essuman VA, Ntim-Amponsah CT, Astrup BS, Adjei GO, Kurtzhals JA, Ndanu TA, Goka B
Reference: 
Malaria Journal 2010, 9:232 (12 August 2010)

This study was designed to determine the diagnostic usefulness of retinopathy on ophthalmoscopy in severe malaria syndromes: Cerebral malaria (CM) and non-cerebral severe malaria (non-CM), i.e. malaria with respiratory distress (RD) and malaria with severe anaemia (SA), in Ghanaian children.

Person: 
Country: 

Open Access | Synergy in Efficacy of Fungal Entomopathogens and Permethrin against West African Insecticide-Resistant Anopheles gambiae Mosquitoes

August 12, 2010 - 14:58 -- Kabogo Ndegwa
Author(s): 
Marit Farenhorst, Bart G. J. Knols, Matthew B. Thomas, Annabel F. V. Howard, Willem Takken, Mark Rowland, Raphael N’Guessan
Reference: 
PLoS ONE 5(8): e12081

Combining fungi and permethrin induced a higher impact on mosquito survival than the use of these control agents alone.

Region: 

Open Access | Detection of mixed Plasmodium falciparum & P. vivax infections by nested-PCR in Pakistan, Iran & Afghanistan

August 12, 2010 - 14:25 -- Kabogo Ndegwa
Author(s): 
Sedigheh Zakeri, Qutbuddin Kakar, Faezeh Ghasemi, Ahmad Raeisi, Waqar Butt, Najibullah Safi, Mandana Afsharpad, Muhammad Suleiman Memon, Saber Gholizadeh, Masoud Salehi, Hoda Atta, Ghasem Zamani, Navid Dinparast Djadid
Reference: 
Indian J Med Res 132, July 2010, pp 31-35

The present data suggest the need for improving microscopy diagnosis method and the clinician should also have careful clinical observation, along with the reports on Giemsa-stained thick blood films, particularly in summer time when P. vivax is predominant.

Country: 

Intranasal and intramuscular immunization with Baculovirus Dual Expression System-based Pvs25 vaccine substantially blocks Plasmodium vivax transmission

August 11, 2010 - 13:30 -- Patrick Sampao
Author(s): 
Andrew M. Blagborough, Shigeto Yoshida, Jetsumon Sattabongkot, Takafumi Tsuboi, Robert E. Sinden
Reference: 
Vaccine, Volume 28, Issue 37, 23 August 2010, Pages 6014-6020

This study offers a novel tool for the development of malarial transmission-blocking vaccines against the sexual stages of the parasite, using the Baculovirus Dual Expression System that functions as both a subunit, and DNA based vaccine.

Medical Condition: 

Open Access | Reducing Plasmodium falciparum Malaria Transmission in Africa: A Model-Based Evaluation of Intervention Strategies

August 11, 2010 - 13:27 -- Kabogo Ndegwa
Author(s): 
Jamie T. Griffin, T. Deirdre Hollingsworth, Lucy C. Okell, Thomas S. Churcher, Michael White, Wes Hinsley, Teun Bousema, Chris J. Drakeley, Neil M. Ferguson, María-Gloria Basáñez, Azra C. Ghani
Reference: 
PLoS Med 7(8): e1000324

Interventions using current tools can result in major reductions in P. falciparum malaria transmission and the associated disease burden in Africa.

Continent: 
Medical Treatment: 

Open Access | Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development

August 11, 2010 - 13:10 -- Kabogo Ndegwa
Author(s): 
Michelle J. Boyle, Danny W. Wilson, Jack S. Richards, David T. Riglar, Kevin K. A. Tetteh, David J. Conway, Stuart A. Ralph,Jake Baum, James G. Beeson
Reference: 
PNAS 2010 Vol 107 No 32 14378-14383

During blood-stage infection by Plasmodium falciparum, merozoites invade RBCs.

Medical Treatment: 

Open Access | Immunoglobulin GM 3 23 5,13,14 phenotype is strongly associated with IgG1 antibody responses to Plasmodium vivax vaccine candidate antigens PvMSP1-19 and PvAMA-1

August 11, 2010 - 13:03 -- Kabogo Ndegwa
Author(s): 
Pandey JP, Morais CG, Fontes CJ, Braga EM
Reference: 
Malaria Journal 2010, 9:229 (9 August 2010)

Results presented here show that immunoglobulin GM allotypes contribute to the natural antibody responses to P. vivax malaria antigens. These findings have important implications for the effectiveness of vaccines containing PvAMA-1 or PvMSP1-19 antigens.

Person: 
Medical Condition: 
Medical Treatment: 

Open Access | Anopheles larval abundance and diversity in three rice agro-village complexes Mwea irrigation scheme, central Kenya

August 11, 2010 - 12:47 -- Kabogo Ndegwa
Author(s): 
Mwangangi JM, Shililu J, Muturi EJ, Muriu S, Jacob B, Kabiru EW, Mbogo CM, Githure J, Novak RJ
Reference: 
Malaria Journal 2010, 9:228 (9 August 2010)

These results suggest that agricultural practices have significant influence on mosquito species diversity and abundance and that certain habitat characteristics favor production of malaria vectors.

Country: 

Pages

Subscribe to Scientific Articles