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Scientific Articles

Small-scale field evaluation of the efficacy and residual effect of Fludora® Fusion (mixture of clothianidin and deltamethrin) against susceptible and resistant Anopheles gambiae populations from Benin, West Africa

January 2, 2019 - 15:34 -- Open Access
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Author(s): 
Fiacre R. Agossa, Gil G. Padonou, Martin C. Akogbeto, et al.
Reference: 
Malaria Journal 2018 17:484, 29 December 2018

Both the Fludora® Fusion combination and clothianidin alone showed very good and lasting efficacy for IRS against resistant Anopheles with some residual benefit provided by the combination.

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Heterogeneous distribution of k13 mutations in Plasmodium falciparum in Laos

January 2, 2019 - 15:33 -- Open Access
Author(s): 
Moritoshi Iwagami, Masami Nakatsu, Shigeyuki Kano, et al.
Reference: 
Malaria Journal 2018 17:483, 27 December 2018

Artemisinin resistance was observed to be rapidly increasing and spreading northwards through Laos and has now reached the Chinese border.

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The effect of mobile phone text message reminders on health workers’ adherence to case management guidelines for malaria and other diseases in Malawi: lessons from qualitative data from a cluster-randomized trial

January 2, 2019 - 15:31 -- Open Access
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Author(s): 
Blessings N. Kaunda-Khangamwa, Laura C. Steinhardt, Alexander K. Rowe, Austin Gumbo, Dubulao Moyo, Humphreys Nsona, Peter Troell, Dejan Zurovac and Don Mathanga
Reference: 
Malaria Journal 2018 17:481, 19 December 2018

Text-message reminders to HWs can provide a platform to improve understanding of treatment guidelines and case management decision-making skills, but might not improve actual adherence to guidelines.

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Subpatent malaria in a low transmission African setting: a cross-sectional study using rapid diagnostic testing (RDT) and loop-mediated isothermal amplification (LAMP) from Zambezi region, Namibia

January 2, 2019 - 15:30 -- Open Access
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Author(s): 
Patrick McCreesh, Davis Mumbengegwi, Michelle S. Hsiang, et al.
Reference: 
Malaria Journal 2018 17:480, 19 December 2018

This study presents results from the first large-scale malaria cross-sectional survey from Namibia using molecular testing to characterize subpatent infections.

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Caregiver responses and association with delayed care-seeking in children with uncomplicated and severe malaria

January 2, 2019 - 15:21 -- Open Access
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Author(s): 
Arthur Mpimbaza, Anne Katahoire, Philip J. Rosenthal, Charles Karamagi and Grace Ndeezi
Reference: 
Malaria Journal 2018 17:476, 18 December 2018

Caregivers should be educated on the importance of promptly seeking care at a health facility where appropriate care can be provided.

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Genetic association between the Pfk13 gene mutation and artemisinin resistance phenotype in Plasmodium falciparum isolates from Yunnan Province, China

January 2, 2019 - 15:20 -- Open Access
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Author(s): 
Ying Dong, Jian Wang, Aiming Sun, Yan Deng, Mengni Chen, Yanchun Xu and Jingpo Xue
Reference: 
Malaria Journal 2018 17:478, 18 December 2018

Although the Plasmodium isolates from Yunnan Province and those from Myanmar were collected from different sites, they still belong to the same geographical population.

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Using the human blood index to investigate host biting plasticity: a systematic review and meta-regression of the three major African malaria vectors

January 2, 2019 - 15:19 -- Open Access
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Author(s): 
James Orsborne, Luis Furuya-Kanamori, Laith Yakob, et al.
Reference: 
Malaria Journal 2018 17:479, 18 December 2018

These findings call into question the appropriateness of current methods of assessing host preferences among disease vectors and have important implications for strategizing vector control.

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Diagnostic performance of salivary urea nitrogen dipstick to detect and monitor acute kidney disease in patients with malaria

January 2, 2019 - 15:17 -- Open Access
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Author(s): 
Viviane Calice-Silva, Euclides Sacomboio, Roberto Pecoits-Filho, et al.
Reference: 
Malaria Journal 2018 17:477, 18 December 2018

The SUN dipstick had reasonable sensitivity and excellent specificity when used to diagnose KD in a cohort of patients with malaria in a resource-limited setting.

Host genetic polymorphisms and serological response against malaria in a selected population in Sri Lanka

January 2, 2019 - 15:16 -- Open Access
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Author(s): 
Rajika L. Dewasurendra, Anna Jeffreys, Sharmini A. Gunawardena, Naduviladath V. Chandrasekharan, Kirk Rockett, Dominic Kwiatkowski and Nadira D. Karunaweera
Reference: 
Malaria Journal 2018 17:473, 17 December 2018

The study suggests that several SNPs in the human genome that exist in Sri Lankan populations are significantly associated with anti-malarial antibodies, either with generation and/or maintenance of antibodies for longer periods, which can be due to either individual polymorphisms or most probably a combined effect of the markers.

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Community facilitators and barriers to a successful implementation of mass drug administration and indoor residual spraying for malaria prevention in Uganda: a qualitative study

January 2, 2019 - 15:14 -- Open Access
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Author(s): 
Humphrey Wanzira, Susan Naiga, Ronald Mulebeke, Fred Bukenya, Mariam Nabukenya, Osborn Omoding, Dorothy Echodu and Adoke Yeka
Reference: 
Malaria Journal 2018 17:474, 17 December 2018

This study documents important community engagement strategies that need to be considered when implementing malaria MDA in combination with IRS, for malaria prevention in such settings.

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