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Scientific Articles

Peek-Peak-Pique: Repeating Motifs of Subtle Variance Are Targets for Potent Malaria Antibodies

May 17, 2018 - 16:02 -- Open Access
Author(s): 
Stephen W. Scally, Jean-Philippe Julien
Reference: 
Immunity, Volume 48, Issue 5, 15 May 2018, Pages 851–854

Biomedical interventions to curb malaria-causing Plasmodium falciparum (Pf) infections are critically needed.

NOT Open Access | Odorant-binding protein-based identification of natural spatial repellents for the African malaria mosquito Anopheles gambiae

May 17, 2018 - 16:01 -- NOT Open Access
Author(s): 
Thomas Kröber, Konstantinos Koussis, Patrick M. Guerin, et al.
Reference: 
Insect Biochemistry and Molecular Biology, Volume 96, May 2018, Pages 36-50

There is increasing interest in the development of effective mosquito repellents of natural origin to reduce transmission of diseases such as malaria and yellow fever.

Microclimate variables of the ambient environment deliver the actual estimates of the extrinsic incubation period of Plasmodium vivax and Plasmodium falciparum: a study from a malaria-endemic urban setting, Chennai in India

May 17, 2018 - 15:33 -- Open Access
Author(s): 
Shalu Thomas, Sangamithra Ravishankaran, Alex Eapen, et al.
Reference: 
Malaria Journal 2018 17:201, 16 May 2018

This study provides a detailed picture of the actual microclimates experienced by mosquitoes in an urban slum malaria setting.

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The impact of the scale-up of malaria rapid diagnostic tests on the routine clinical diagnosis procedures for febrile illness: a series of repeated cross-sectional studies in Papua New Guinea

May 17, 2018 - 15:32 -- Open Access
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Author(s): 
Justin Pulford, Serah Kurumop, Ivo Mueller, Peter M. Siba and Manuel W. Hetzel
Reference: 
Malaria Journal 2018 17:202, 16 May 2018

Rapid diagnostic tests scale-up has led to a reduction in body temperature measurement. Investigations are very limited when malaria infection is ruled out as a cause of febrile illness by RDT.

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Provider and patient perceptions of malaria rapid diagnostic test use in Nigeria: a cross-sectional evaluation

May 17, 2018 - 15:30 -- Open Access
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Author(s): 
Olugbenga A. Mokuolu, Olufemi O. Ajumobi, Bala M. Audu, et al.
Reference: 
Malaria Journal 2018 17:200, 16 May 2018

The study demonstrated positive perception to RDT use by HW and among community members with good compliance rate among health workers at the PHC level.

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Medical Treatment: 

Disentangling complex parasite interactions: Protection against cerebral malaria by one helminth species is jeopardized by co-infection with another

May 15, 2018 - 15:02 -- Open Access
Author(s): 
Jessica L. Abbate, Vanessa O. Ezenwa, Jean-François Guégan, Marc Choisy, Mathieu Nacher, Benjamin Roche
Reference: 
PLoS Negl Trop Dis 12(5): e0006483

Multi-species interactions can often have non-intuitive consequences.

Modeling the impact of Plasmodium falciparum sexual stage immunity on the composition and dynamics of the human infectious reservoir for malaria in natural settings

May 15, 2018 - 15:00 -- Open Access
Author(s): 
André Lin Ouédraogo, Philip A. Eckhoff, Adrian J. F. Luty, Will Roeffen, Robert W. Sauerwein, Teun Bousema, Edward A. Wenger
Reference: 
PLoS Pathog 14(5): e1007034

Malaria transmission remains high in Sub-Saharan Africa despite large-scale implementation of malaria control interventions.

Outcome of capacity building intervention for malaria vector surveillance, control and research in Nigerian higher institutions

May 15, 2018 - 14:50 -- Open Access
Tags: 
Author(s): 
Adedayo O. Oduola, Abiodun Obembe, Olukayode J. Adelaja, Adeniyi K. Adeneye, Joel Akilah and Taiwo S. Awolola
Reference: 
Malaria Journal 2018 17:193, 15 May 2018

The capacity available for vector control research and surveillance at institutional level in Nigeria is weak and require further strengthening.

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Phenotypic and genotypic characterization of Thai isolates of Plasmodium falciparum after an artemisinin resistance containment project

May 15, 2018 - 14:45 -- Open Access
Author(s): 
Thunyapit Thita, Pimrat Jadsri, Jarupatr Thamkhantho, Toon Ruang-areerate, Nantana Suwandittakul, Naruemon Sitthichot, Kittiya Mahotorn, Peerapan Tan-ariya and Mathirut Mungthin
Reference: 
Malaria Journal 2018 17:197, 15 May 2018

Although the containment project had been implemented in this area, the expansion of artemisinin-resistant parasites did not decline.

Pyronaridine–artesunate and artemether–lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Kenyan children: a randomized controlled non-inferiority trial

May 15, 2018 - 14:43 -- Open Access
Author(s): 
Johanna M. Roth, Patrick Sawa, Nicodemus Makio, George Omweri, Victor Osoti, Selpha Okach, Felix Choy, Henk D. F. H. Schallig and Pètra Mens
Reference: 
Malaria Journal 2018 17:199, 15 May 2018

Pyronaridine–artesunate was well tolerated, efficacious and non-inferior to artemether–lumefantrine for the treatment of uncomplicated P. falciparum malaria in Kenyan children.

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