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Scientific Articles

In silico epitope mapping and experimental evaluation of the Merozoite Adhesive Erythrocytic Binding Protein (MAEBL) as a malaria vaccine candidate

January 13, 2018 - 14:24 -- Open Access
Author(s): 
Pedro Cravo, Renato B. Machado, Fabio T. M. Costa, et al.
Reference: 
Malaria Journal 2018 17:20, 10 January 2018

The MAEBL antigen is promising candidate towards the development of a malaria vaccine.

Malaria programme personnel’s experiences, perceived barriers and facilitators to implementing malaria elimination strategy in South Africa

January 13, 2018 - 14:22 -- Open Access
Tags: 
Author(s): 
Khumbulani Welcome Hlongwana, Benn Sartorius and Joyce Tsoka-Gwegweni
Reference: 
Malaria Journal 2018 17:21, 10 January 2018

Most participants were not positive that South Africa could achieve the malaria elimination goal by 2018, citing the high cross-border movements and lack of resources as key barriers.

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An observational analysis of the impact of indoor residual spraying with non-pyrethroid insecticides on the incidence of malaria in Ségou Region, Mali: 2012–2015

January 13, 2018 - 14:16 -- Open Access
Author(s): 
Joseph Wagman, Christelle Gogue, Molly Robertson, et al.
Reference: 
Malaria Journal 2018 17:19, 10 January 2018

From 2012 to 2015, the annual IRS campaigns in Ségou are associated with several hundred thousand fewer cases of malaria.

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Medical Treatment: 

Diagnostic challenges of prolonged post-treatment clearance of Plasmodium nucleic acids in a pre-transplant autosplenectomized patient with sickle cell disease

January 13, 2018 - 14:14 -- Open Access
Author(s): 
Paul M. Luethy, Sean C. Murphy, Annette M. Seilie, Yingda L. Xie, Chuen-Yen Lau, John F. Tisdale, Matthew M. Hsieh, Jessica L. Reinhardt, Anna F. Lau and Gary A. Fahle
Reference: 
Malaria Journal 2018 17:23, 10 January 2018

While molecular testing can provide sensitive Plasmodium nucleic acid detection, the persistence of Plasmodium nucleic acids following adequate treatment in functionally asplenic patients can lead to a diagnostic dilemma.

Attractive toxic sugar baits for controlling mosquitoes: a qualitative study in Bagamoyo, Tanzania

January 13, 2018 - 14:12 -- Open Access
Author(s): 
Marta Ferreira Maia, Frank Chelestino Tenywa, Hannah Nelson, Athumani Kambagha, Abigail Ashura, Ibrahim Bakari, Deogratis Mruah, Aziza Simba and Ally Bedford
Reference: 
Malaria Journal 2018 17:22, 10 January 2018

This study delivers insight on how communities in Coastal Tanzania are likely to perceive ATSBs and provides important information for future trials investigating the efficacy of ATSBs against malaria.

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NOT Open Access | Neurological involvement associated with Plasmodium vivax malaria from Pakistan

January 10, 2018 - 15:52 -- NOT Open Access
Author(s): 
Yousaf Abdullah Khan, Usman Hameed Mian, Najia Karim Ghanchi, Ali Bin Sarwar Zubairi, and Mohammad Asim Beg
Reference: 
Tropical Doctor, vol. 48, 1: pp. 52-54

Plasmodium vivax is the most common specie causing malaria outside Africa with approximately 13.8 million reported cases worldwide.

Why do people participate in mass anti-malarial administration? Findings from a qualitative study in Nong District, Savannakhet Province, Lao PDR (Laos)

January 10, 2018 - 15:41 -- Open Access
Tags: 
Author(s): 
Bipin Adhikari, Koukeo Phommasone, Christopher Pell, et al.
Reference: 
Malaria Journal 2018 17:15, 9 January 2018

Future malaria control programmes can become successful in achieving the high coverage in MDAs drawing from the success of TME in Laos

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Global sequence diversity of the lactate dehydrogenase gene in Plasmodium falciparum

January 10, 2018 - 15:40 -- Open Access
Author(s): 
Phumin Simpalipan, Sittiporn Pattaradilokrat and Pongchai Harnyuttanakorn
Reference: 
Malaria Journal 2018 17:16, 9 January 2018

This study revealed the global genetic variation of the ldh gene in P. falciparum, providing knowledge for improving detection of LDH-based RDTs and supporting the candidacy of LDH as a therapeutic drug target.

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Differential induction of malaria liver pathology in mice infected with Plasmodium chabaudi AS or Plasmodium berghei NK65

January 10, 2018 - 15:38 -- Open Access
Author(s): 
Diletta Scaccabarozzi, Katrien Deroost, Yolanda Corbett, Natacha Lays, Paola Corsetto, Fausta Omodeo Salè, Philippe E. Van den Steen and Donatella Taramelli
Reference: 
Malaria Journal 2018 17:18, 9 January 2018

This study demonstrates that in C57BL/6J mice, depending on the parasite species, malaria-induced liver pathology results in different manifestations, which may contribute to the different outcomes.

Medical Condition: 

Molecular identification of sulfadoxine-pyrimethamine resistance in malaria infected women who received intermittent preventive treatment in the Democratic Republic of Congo

January 10, 2018 - 15:36 -- Open Access
Author(s): 
Emrah Ruh, Jean Paul Bateko, Turgut Imir and Aysegul Taylan-Ozkan
Reference: 
Malaria Journal 2018 17:17, 9 January 2018

In the study, the rate of SGEGA haplotype was low (2.1%). Although K540E and A581G alleles are more common in Eastern Africa, a distinct lineage of SGEGA is also present in the DRC, which is located in Central Africa.

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