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Scientific Articles

Comparison of three diagnostic methods (microscopy, RDT, and PCR) for the detection of malaria parasites in representative samples from Equatorial Guinea

September 18, 2018 - 16:17 -- Open Access
Author(s): 
Pedro Berzosa, Aida de Lucio, Agustín Benito, et al.
Reference: 
Malaria Journal 2018 17:333, 17 September 2018

Owing to the high number of false negatives in microscopy, it is necessary to reinforce training in microscopy, the “Gold Standard” in endemic areas.

The prevalence of submicroscopic Plasmodium falciparum gametocyte carriage and multiplicity of infection in children, pregnant women and adults in a low malaria transmission area in Southern Ghana

September 18, 2018 - 16:15 -- Open Access
Author(s): 
Helena Lamptey, Michael Fokuo Ofori, Isabella A. Quakyi, et al.
Reference: 
Malaria Journal 2018 17:331, 17 September 2018

These findings suggest that children and pregnant women are particularly important as P. falciparum submicroscopic gametocyte reservoirs and represent important focus groups for control interventions.

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Analysis of clinical malaria disease patterns and trends in Vietnam 2009–2015

September 18, 2018 - 16:14 -- Open Access
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Author(s): 
Kinley Wangdi, Sara E. Canavati, Thang Duc Ngo, Long Khanh Tran, Thu Minh Nguyen, Duong Thanh Tran, Nicholas J. Martin and Archie C. A. Clements
Reference: 
Malaria Journal 2018 17:332, 17 September 2018

Interventions (ITN distribution) and environmental factors (increased temperature) were associated with incidence of P. falciparum and P. vivax during the study period.

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The quality of anti-malarial medicines in Embu County, Kenya

September 18, 2018 - 16:11 -- Open Access
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Author(s): 
Stanley Ndwigah, Andy Stergachis, Kennedy Abuga, Hannington Mugo and Isaac Kibwage
Reference: 
Malaria Journal 2018 17:330, 15 September 2018

All the anti-malarial drugs analysed in this study passed the quality control tests.

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NOT Open Access | cGMP Signalling: Malarial Guanylyl Cyclase Leads the Way

September 13, 2018 - 17:27 -- NOT Open Access
Author(s): 
Mathieu Brochet
Reference: 
Current Biology Volume 28, Issue 17, 10 September 2018, Pages R939-R941

When ingested by a mosquito, the malaria parasite relies on an unusual form of gliding motility to escape from the rapidly deteriorating blood meal.

Prevalence of asymptomatic Plasmodium infections with sub-microscopic parasite densities in the northwestern border of Thailand: a potential threat to malaria elimination

September 13, 2018 - 17:25 -- Open Access
Author(s): 
Jetsumon Sattabongkot, Chayanut Suansomjit, Wang Nguitragool, Jeeraphat Sirichaisinthop, Saradee Warit, Montip Tiensuwan and Sureemas Buates
Reference: 
Malaria Journal 2018 17:329, 12 September 2018

Participants carrying asymptomatic Plasmodium infections with sub-microscopic parasite densities are considerable in this area.

IgG subclass responses to excreted-secreted antigens of Plasmodium falciparum in a low-transmission malaria area of the Peruvian Amazon

September 11, 2018 - 14:58 -- Open Access
Author(s): 
Rafael Saavedra-Langer, Jorge Marapara, Andree Valle-Campos, Salomón Durand, Maria E. Vásquez-Chasnamote, Hermann Silva and Viviana Pinedo-Cancino
Reference: 
Malaria Journal 2018 17:328, 11 September 2018

This is the first study that characterizes the IgG subclass response in the Peruvian Amazon, and these results show that even in populations from regions with low malaria transmission, a certain degree of naturally acquired immunity can develop when the right antibody subclasses are produced.

Increasing women’s engagement in vector control: a report from Accelerate To Equal project workshops

September 11, 2018 - 14:56 -- Open Access
Tags: 
Author(s): 
Kacey C. Ernst, Erika Barrett, Elizabeth Hoswell and Mary H. Hayden
Reference: 
Malaria Journal 2018 17:326, 10 September 2018

Workshops with academic, national and local government, and community stakeholders were held in Kenya (2017) and Indonesia (2018) to understand the role and perceptions of women in vector control and to identify strategies for accelerating involvement of women in sustained support for vector control interventions at multiple levels/sectors.

Optimization of a magnetic bead-based assay (MAGPIX®-Luminex) for immune surveillance of exposure to malaria using multiple Plasmodium antigens and sera from different endemic settings

September 11, 2018 - 14:55 -- Open Access
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Author(s): 
Marie Louise Varela, Babacar Mbengue, Aissata Basse, Cheikh Loucoubar, Inès Vigan-Womas, Alioune Dièye, Aissatou Toure and Ronald Perraut
Reference: 
Malaria Journal 2018 17:324, 6 September 2018

This study underlines the importance of further optimization of the MBA technique and highlights the interest of using multistage/multispecies antigens for surveillance of malaria in endemic settings.

NOT Open Access | Malaria parasite translocon structure and mechanism of effector export

September 11, 2018 - 14:53 -- NOT Open Access
Tags: 
Author(s): 
Chi-Min Ho, Josh R. Beck, Mason Lai, Yanxiang Cui, Daniel E. Goldberg, Pascal F. Egea & Z. Hong Zhou
Reference: 
Nature volume 561, pages70–75 (2018)

The putative Plasmodium translocon of exported proteins (PTEX) is essential for transport of malarial effector proteins across a parasite-encasing vacuolar membrane into host erythrocytes, but the mechanism of this process remains unknown.

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