No exacerbation from co-infection with Plasmodium and helminths was observed, neither in participants aged 5–18 years nor in adults from the community-based studies.
This study confirms that in malaria endemic settings, sub-patent malaria infections among blood donors are prevalent.
The current study demonstrates that the XN-30 analyzer objectively, reproducibly, and easily evaluated and characterized the anti-malarial efficacy of various compounds.
These results indicate that SNP rs2910164 G > C is associated with increased odds for P. falciparum infection in first-time pregnant women who are considered to lack sufficient acquired immune responses against pregnancy-specific strains of P. falciparum.
While the importance of understanding human-vector interaction is well-established, relatively few studies have included human behaviour when measuring exposure to malaria vectors.
Improving the quality of treatment is essential to combat the burden of malaria and prevent the development of drug resistance.
For this update, two review authors independently re‐extracted all data and assessed certainty of evidence. We meta‐analysed data to calculate risk ratios (RRs) for treatment failures between comparisons, and for safety outcomes between and across comparisons.
The gametocyte sexual form of Plasmodium falciparum, a parasite that causes human malaria, is responsible for mosquito-borne transmission of infection. Some individuals carry low concentrations of the parasite (subclinical infection), which makes detection and eradication difficult. Tao et al. developed a rapid lateral flow assay that detects a female gametocyte-specific protein, PSSP17, in saliva.
Genetic manipulation remains a major obstacle for understanding the functional genomics of the deadliest malaria parasite Plasmodium falciparum.
Lipoate is a redox active cofactor that is covalently bound to key enzymes of oxidative metabolism.