The world's scientific and social network for malaria professionals
9354 malaria professionals are enjoying the free benefits of MalariaWorld today

GCE Special: Development of an RNAi based microalgal larvicide to control mosquitoes

May 27, 2013 - 19:45 -- Bart G.J. Knols
Author(s): 
Anil Kumar, Songjie Wang, Ruguang Ou, Mustapha Samrakandi, Brenda T. Beerntsen, Richard T. Sayre
Reference: 
MWJ 2013, 4, 6
Article type: 
Research
Abstract: 

This GCE project explored an RNAi strategy to control mosquitoes and prevent spread of mosquito-borne diseases. The strategy involved delivery of double-stranded RNA(dsRNA) elements to mosquito larvae using unicellular, transgenic algae as vectors. Significantly, microorganisms, including microalgae, are the primary source of nutrition for mosquito larvae in water bodies that serve as the breeding grounds for mosquitoes. This strategy of delivering RNA elements to suppress essential target genes in mosquito larvae has many potential advantages over existing technologies.

 
AttachmentSize
PDF icon MWJ2013_4_6.pdf850.92 KB