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Last week at MalariaWorld: WHO Report on antimalarial drug efficacy, resistance and response, more news from ASTMH 2020 conference, and more...

November 26, 2020 - 19:55 -- Ingeborg van Schayk

WHO Report

WHO Report on antimalarial drug efficacy, resistance and response: 10 years of surveillance (2010–2019)

The 'Report on antimalarial drug efficacy, resistance and response: 10 years of surveillance (2010–2019)' presents a decade’s worth of data on drug efficacy and surveillance, as well as recommendations to monitor  and protect the efficacy of malaria treatment in the decades to come. A brochure that includes the main findings, key definitions and background information for non-experts complements the report.
Download the report & brochure here

New from MESA

MESA Correspondents reporting from the ASTMH 2020 Annual Meeting (virtual)


Day 3: Tuesday, 17th November 2020

The malaria-related symposiums covered by the MESA Correspondents for the third day of the ASTMH 2020 are on:

  • Basic Research in Africa for Sustained Malaria Elimination and Eradication
  • Human Challenge Infections: Learning from Nature in Controlled Settings

Silvia N. Kariuki (KEMRI-Wellcome, Kenya) gave a riveting talk titled “Red blood cell tension protects against severe malaria in the blood group variant Dantu”...

Read the full report of Day 3


Day 4: Wednesday, 18th November 2020

On Wednesday, November 18th, the MESA Correspondents reported from the following sessions:

  • Ivermectin and Antimalarial Mass Drug Administration for Malaria Control and Elimination: Preliminary Field Trial Results and Trial Designs
  • Lessons from the National Malaria Elimination Program in China
  • Monoclonal Antibodies to Prevent Malaria Infection and Transmission – From Antibody Identification to Clinical Evaluation
  • Towards Regional Elimination of Malaria in Central America
  • Host-Directed Therapeutics for Malaria
  • Severe Malaria: Improving the Continuum of Care
  • Accelerating New Tools for Radical Cure of vivax Malaria from Clinical and Operational Research to Policy
  • Using the Data You Have: Innovative Methods to Enhance Vector Control Evaluation and Decision-Making

Umberto D’Alessandro (MRC Unit The Gambia at the London School of Hygiene and Tropical Medicine Disease Control & Elimination Theme, Gambia) presented his work on combined mass drug administration (MDA) of ivermectin and dihydroartemisinin-piperaquine (DHA-PQ) as a potential intervention for malaria elimination in communities in The Gambia with high coverage of other vector control interventions...

Read the full report of Day 4


Day 5: Thursday, 19th November 2020

On Thursday, November 19th, the MESA Correspondents reported from the following sessions:

  • Vaccines Against Placental Malaria
  • Cross-Disciplinary Sciences to Understand Malaria Vaccine Immunity
  • Spatial Intelligence to Optimize Public Health Interventions
  • Responding to the challenge of vector-borne diseases in the context of urban expansion
  • Integrating Functional, Population Genomic and Transcriptomic Data to Decipher Antimalarial Drug Resistance and Guide Drug Discovery
  • Current Knowledge of Mosquito-Stage Malaria Parasite Biology: Implications for Developing a Robust in vitro Culturing System
  • Tracking the Threat of pfhrp2/3 Gene Deletions and Future Alternatives to HRP2-based Malaria Diagnosis

Arnaud Chȇne (French Institute of Health and Medical Research, Paris, France) updated the audience on progress in the development of a placental malaria vaccine. About 30 million women become pregnant in malaria-endemic areas annually, and this malaria-susceptible group requires some form of protection.

Read the full report of Day 5


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This weeks Malaria Minute Podcast


Conserved Antigen Pb22 Plays a Critical Role in Male Gametogenesis in P. Berghei
Pb22, a protein expressed by Plasmodium berghei, may play an important role in the transmission of malaria, and review on the use of tafenoquine finds that the drug is well-tolerated and effective.
Listen to this Podcast

Global malaria news

Mosquitoes carry more malaria parasites depending on when they bite
New Scientist, 25 November 2020
When a malaria-infected bird is bitten by mosquitoes over the course of 3 hours, the first insects to feed end up carrying fewer malaria parasites than those that feed later – and the same may apply when infected people are bitten.
Read this article


Children as superspreaders of malaria
Devex, 19 November 2020
ew research from Uganda found that asymptomatic, school-aged children can serve as superspreaders of malaria. These findings suggest that efforts to eliminate the disease from countries might be harder than previously thought.
Read this article


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Scientific Publications

During the past week dozens of new scientific malaria publications were published on MalariaWorld

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