Last week at MalariaWorld: Job opportunity, ASTMH reports, blogs, and more...
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Congratulations Rose
Rose Leke, Emeritus Professor of Immunology and Parasitology at the University of Yaoundé, Cameroon has been awarded the Clara Ludlow Medal by the American Society of Tropical Medicine and Hygiene (ASTMH) during its recent annual meeting. This award recognises honorees for their inspirational and pioneering spirit, whose work represents success despite obstacles and advances the field of tropical medicine. Rose, indeed, is a remarkable woman. Let me tell you why.
Back in the year 2000, I was appointed by the US National Library of Medicine (NLM) as the Communications Director of the Multilateral Initiative on Malaria (MIM). NLM was connecting 19 malaria research institutes throughout Africa to the internet. I decided to investigate the impact of internet access on malaria research as well as on the performance of malaria institutes. Reliable internet was new (and heavenly) and a whole new world of opportunities opened up to us. Now we could organise a symposium in rural Kenya and invite people by email! And invitees would receive their invitation on time and could actually make it to us on time. And image that access to the internet allowed us to be notified about grant opportunities and we could finally submit a grant proposal on time by email rather than snail mail. This all had a significant impact. But as we were all 'new' to the virtual world, only few people knew how to 'google' information. I noticed that malaria professionals all over Africa were spending hours and hours per week to search for the same information. That is when we started with a small team to collect scientific information on malaria and shared that with other malaria professionals, like yourself. In those days Rose had a senior position at the University of Yaoundé, one of the 19 centres in our network. That's how we met. She was among the very first scientists to sign up for our information service called 'the MIMCom Malaria News Update' that eventually evolved into what is now MalariaWorld. And whenever I would meet Rose somewhere around the world she would tell me how important she believed the work of MalariaWorld is. I am proud to say that Rose Leke stood at the cradle of MalariaWorld. On behalf of the entire MalariaWorld team I wholeheartedly congratulate Rose with this so well deserved award!
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Job: Vacancy for a Post-Doctoral Research Associate in Molecular Entomology at LSTM
The department of Vector Biology at the Liverpool School of Tropical Medicine (UK) has an opportunity for a highly motivated Post–Doctoral Research Associate to bring their expertise and enthusiasm to an inter-disciplinary project on the role of Anopheles stephensi in malaria transmission in the Horn of Africa. Closing date for applications is 12th December 2021.
Read more and how to apply
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MESA Correspondents reporting from the ASTMH 2021 Annual Meeting (virtual)
Day 4: Saturday, November 20 - the MESA Correspondents reported from the following sessions:
- Symposium #85: Malarial Immune Response from Numerous Perspectives. Speakers: Teun Bousema, Jason Nideffer, Clinton Onyango, Isobel Walker, Lauren Bradley, Wael Abdrabou and Fergal Duffy.
- Symposium #88: Malaria: Genetics, Genomics and Modeling. Speakers: Sachel Mok, Sudhir Kumar, Angela Early, Jessica Ribado, Joshua Suresh and Branwen Owen.
- Symposium #93: Intermittent Preventive Treatment for Malaria in Infants with Sulfadoxine - Pyrimethamine (SP-IPTi): Fit for Purpose in 2021? Speakers: Clara Menéndez, Dorothy Kah Fosah Achu, Olusola Oresanya and Sian Clarke.
- Symposium #102: Ex Vivo Assessment of Drug Susceptibility of the Antimalarial Drug Pipeline. Speakers: Oriana Kreutzfeld, Laurent Dembelé, Camille Roesch and Caroline Aguiar.
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Day 5: Sunday, November 21 - the MESA Correspondents reported from the following sessions:
- Symposium #119: Integrating Molecular Data into Malaria Surveillance: Progress in Senegal. Speakers: Fatou Ba Fall, July Thwing, Aida Badiane and Caitlin Bever.
- Symposium #125: Dihydroartemisinin-piperaquine as an Alternative Drug for Intermittent Preventive Treatment for the Control of Malaria in Pregnancy in Areas of High Sulphadoxine - Pyrimethamine Resistance in East and Southern Africa. Speakers: Mwayiwawo Madanitsa, Feito ter Kuile, Michelle Roh and Julie Gutman.
- Symposium #130: Expanding the Use of Safe and Effective Radical Cure of Relapsing Malaria: Defining Populations at Risk of Hemolysis. Speakers: Ari Winasti Satyagraha, Benedikt Ley, James Watson and Cindy Chu.
- Symposium #136: Implementing Malaria Chemoprevention Campaigns During the COVID-19 Pandemic. Speakers: Abimbola Phillips, Assane Kano, Seynabou Gaye and Pedro Aide.
- Symposium #140: Eliminating Malaria in the Guiana Shield During COVID-19 Times: How Can We Accelerate It? Speakers: Leopoldo Villegas, Horace Cox, Lise Musset and Helene Hiwat.
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The reports from Day 1,2 and 3 were published in last week's newsletter. Please find these reports here:
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Blog Posts
Blog: Homologous P. vivax malarial recurrences are not necessarily relapses
By Miles Markus
It was pointed out a decade ago that non-reinfection recurrences of Plasmodium vivax malaria caused by parasites that are closely related to those from an earlier time point are highly suggestive of a merozoite origin. This would make them recrudescences (in an unknown proportion of cases), not relapses. In other words, hypnozoites have nothing to do with such a recurrence. Some recurrences that take place after 28 days post infection are also recrudescences (not relapses), as has recently been explained.
Read this blog
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Blog: Can P. vivax sporozoites having the same genotype be both tachysporozoites and bradysporozoites?
By Miles Markus
Lysenko et al.’s hypothetical P. vivax tachysporozoites multiply in the liver soon after inoculation into the host, whereas their hypothetical bradysporozoites form hypnozoites, which are the origin of relapses. This "tachy" and "brady" terminology is an extension of usage unrelated to malaria. For a homologous P. vivax malarial recurrence to be a relapse means that firstly, a tachysporozoite(s) will have had to initiate what became a patent infection. But it also means that a sister sporozoite(s) with basically the same genotype must have been, simultaneously, a bradysporozoite(s). This is how hypnozoite-derived recurrent parasites in the bloodstream could in theory come to be genotypically similar to those from an earlier time point. However, do different sporozoites having the same genotype in fact act inconsistently by functioning as either tachysporozoites or bradysporozoites?
Read this blog
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Scientific Publications
During the past week dozens of new scientific malaria publications were published on MalariaWorld
Read the latest scientific malaria publications here
Enjoy this week's MalariaWorld - the MW team
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