Reply to: Artequick: programmed for failure
A year ago a blog posted by Irene Teis where she asked if Artequick was programmed for failure had raised a violent debate. Bangaly Danfakha stated that this was a false, disgraceful claim. Anton Alexander was saddened by this outburst. Pierre Lutgen quoted a document published by CBS NEWS on November 11, 2014 under the title « CHINA TESTS MALARIA DRUG ON AN ENTIRE AFRICAN NATION » in the Comoros and fin’s this approach intriguing, if not unethical.
It appears now that Irene’s concern was valid.
This week a paper by S.Chaorattanakawee in Malaria Journal (Oct 21, 15, 519) informs us that ex vivo piperaquine resistance developed rapidly in Plasmodium falciparum isolates in northern Cambodia. This raises a lot of concern as DHA-PPQ is being introduced as first-line treatment in neighbouring countries.
This urgently requires alternative therapy. The temporary re-introduction of artesunate-mefloquine is the current response. A very bad choice as mefloquine is known for severe psychologic effects and is banned in several countries.
Why not use Artemisia annua infusions or powdered leaves ? The large scale, randomized, double blind clinical trials in RDC have shown a 98% efficacy, no side effects,absence of gametocytes, no recrudescence on day 28.
Reply to: Promoting south-centred collaborations in vector-borne diseases
Good initiative Gerry... I support this. Let me know if I can contribute anything in this.
Manas Sarkar, PhD
SRS (DGM) & Head, Advance Technology & Innovation, Godrej-R&D
Reply to: Artemisinin first discovered by the Serbs long before the Chinese
In fact, the Nobel price should have gone to the African herbalists and healers who in South Africa, Ethiopia, Kenya, Tanzania, Zimbabwe… have been using Artemisia afra long before our media and their continent were swamped by artemisinin chemical derivatives.
Recent trials in RDCongo and elsewhere have confirmed that Artemisia afra is much more potent against malaria than Coartem, Artequick, or Coarsucam, without side effects and without recrudescence.
Already in 1962 a book by John Michell Watt, Breyer Brandwyck, Maria Gerdina (ed Livingstone Edingburgh) showed that Artemisia afra extracts where stronger against PoW and Dd2 Plasmodium falciparum strains than 9 other medicinal plants.
In 1962 !
Reply to: Impact of Anti-DDT Campaigns on Malaria Control
To claim victory in the battle against malaria in Sri Lanka is like GW Bush claiming “Mission accomplished” in Irak after having killed 300 000 inhabitants. From 1930 to 1950 Sri Lanka knew a malaria scurge with an average number of 300 000 cases per year with a massive epidemic of 1934. This may well have served as a major impetus in motivating both the government and the public to intensify control efforts and adoption of DDT spraying in 1945 which led to a marked decline in the malaria case numbers and in 1960 malaria was eradicated. But it returned in 1970 when DDT indoor residual spraying was forbidden. All the fatalities accumulated over the last 40 years in this country are due to the stubborness of Greenpeace refusing to recognize that DDT never had caused any significant health problem to any single human being in any country at any age, but saved millions of lives. The green religion has killed more people than Daech or the Crusades.
Reply to: In memoriam: Anuj Nathalal Shah (1960-2016)
Happy to know about the history and achievement of Anuj Shah in this essay. It's is really a motivation and the way of his achievements is looking great and powerful. Thank you for sharing such a valuable information. We all missed this great personality.