Reply to: Plasmodium is killed by zinc chelators
May I recommend the excellent Paper " Prophylaxis with Artemisia annua is very efficient: the role of chelators
Pharm Pharmacol Int J 2017, 5(5):00138
Reply to: PLASMOBASE: NEW website providing a new protein domain annotation and comparing protein domain architectures of 11 Plasmodium genomes
I just design a work on molecularepidemiology of Plasmodium in a state in Nigeria now with the focus of developing the outcome for vaccine production. Can I get a grant or collaborate with you so I can work in your laboratory.
Reply to: Loop-Mediated Isothermal Amplification Method (LAMP): Low and Effective cost Novel Tool for Molecular Public Health
Good afternoon, I am an undergraduate student and I am using the LAMP technique in my thesis topic, I have some drawbacks with what is standardization and some questions:
1: Does the use of MgCl2 in some way influence MgSO4?
2: Does Betaine need to be added for amplification to perform?
Thank you for your attention, I await your response.
Reply to: Spam: 'We invite you to submit an article to our Open Access journal'
1) Until the world creates a way of subsidising the work of editors, they need to be recompensed.
2) Free publication, free access is obviously ideal.
3) These new journals are meeting the demand to get published, which is a metric that must change before the demand will reduce.
4) Don't blame the journal if they're at least got some standards, and aren't price gouging.
Reply to: How was malaria of 100 years ago eradicated in Palestine/Israel? And without vaccine?
Kligler used simple drainage and filling of mosquito breeding sites as a quick and permanent way to suppress malaria transmission, as Anton Alexander has explained in his article on Kligler in Palestine. These are simple engineering methods available everywhere. They are known under the general title of Larval Source Management, or LSM.
In addition permanent improvements in housing, including metallic screens on doors and windows, and covering of gaps in walls and ceilings will keep anophelines out of houses, and thus prevent biting of sleeping people, and transmission of malaria.
Small electric fans or at least good cross ventilation also disrupts the hunting and feeding activities of the female anophelines.
These methods were successfully used in the USA prior to World War Two, and have been documented extensively in the book 'Control of malaria on impounded waters' US govt printing office in 1947. Please find engineering and architectural colleagues in Zambia to help you and entomologists develop these permanent methods.
And more recently, larval source management methods of several kinds have been used successfully in Tanzania by Fillinger, and also by Marcia de Castro. In this effort they used improved drainage, and also biological agents to kill mosquito larvae.
See this article in the Malaria Journal of 2011; volume 10:page 338.
Published online 2011 Nov 8. doi: 10.1186/1475-2875-10-338
Large-scale use of mosquito larval source management for malaria control in Africa: a cost analysis
by Eve Worrall and Ulrike Fillinger
Look up these articles on the web, or get help from friends in the Ministry of Health or local universities to find them, based on the references I cited above.
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