Etude comparative de l’efficacité in vivo de l’artesunate avec l’amodiaquine et la tisane Artemisia annacultivée à Bangangté à l’Ouest du Cameroun
Chougouo Kengne R.D*., Kouamouo J*., Moyou Somo R**., Penge On’Okoko A***. *Université des Montagnes, Bangangté, Cameroun ; ** IMPM /CRM et FMSB Cameroun; *** Université de Kinshasa RDC.
This work was carried out period of June in October 2006 at the hospital of district of Bangangté It aimed to compare the effectiveness of Artesunate alone, in partnership with Amodiaquine on P. falciparum and the same time study of therapeutic effectiveness of Artemisia annua like plants antimalaria in the department of the NDE. The Artesunate took in 5 days and Artesunate/Amodiaquine association took in 3 days gave 81,25% and 85,70% respectively. The herb tea of Artemisia annua taken in 5 days or 7 days gives the following therapeutic response respectively: 71, 3% and 100%. It is noted that the therapeutic response of herb teas is improved by prolonging the time. Adverse events associated with Artesunate is the sensation of hyperthermia while those related to the association Artesunate / Amodiaquine is mainly myalgia, anorexia,abdominal pain
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Annales de Pharmacie- Université de Kinshasa. 2012, 4-1, 127-148