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diagnosis

GCE Special: Malaria β-Haematin in blood results in synergistic attenuation enhancement: Studies with a conventional multimode reader and a custom LED device

May 27, 2013 - 19:50 -- Bart G.J. Knols
Author(s): 
Eugene Y. Chan, Kristyn Maiorca, Candice Bae, Nathaniel Sharpe, Vinay Tripuraneni, Julia Z. Sharpe
Reference: 
MWJ 2013, 4, 7

The aim of this GCE project was to develop a non-invasive method for diagnosing malaria. In order to do this, we sought to identify a novel optical property of β-haematin that gives it a robust optical signature. The optical signature needs to be readily detected with light-emitting diodes (LEDs) and photodiodes, which are compatible with low-cost operation in the developing world. The product is envisioned to be similar to a commercial fingertip pulse oximeter, which can be purchased for $20 and can be utilised for thousands of tests with a single battery.

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Open Access | Field evaluation of a rapid diagnostic test (ParascreenTM) for malaria diagnosis in the Peruvian Amazon

June 8, 2010 - 09:54 -- Kabogo Ndegwa
Author(s): 
Bendezu J, Rosas A, Grande T, Rodriguez H, Llanos-Cuentas A, Escobedo J, Gamboa D
Reference: 
Malaria Journal 2010, 9:154 (7 June 2010)

The study results indicate that ParascreenTM is not a valid and acceptable test for malaria diagnosis under the field conditions found in the Peruvian Amazon.

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Short Communication: Performance of a prototype malaria rapid diagnostic test versus thick film microscopy among HIV-positive subjects in rural Rakai, Uganda

March 5, 2010 - 11:27 -- Kabogo Ndegwa
Author(s): 
Lisa A. Mills, Joseph Kagaayi, Joseph P. Shott, Kevin Newell, John Baptist Bwanika, Victor Ssempijja, Simon Aluma, Thomas C. Quinn, Steven J. Reynolds, Ronald H. Gray
Reference: 
Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 104, Issue 3, March 2010, Pages 237-239

In this study, we report the performance of a prototype malaria rapid diagnostic test, Malaria F-test (MFT), compared with thick blood films from HIV-positive Ugandans undergoing malaria testing.

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Identification of Malaria Retinopathy Improves the Specificity of the Clinical Diagnosis of Cerebral Malaria: Findings from a Prospective Cohort Study

February 11, 2010 - 13:31 -- Ingeborg van Schayk
Author(s): 
Gretchen L. Birbeck, Nicholas Beare, Susan Lewallen, Simon J. Glover, Malcolm E. Molyneux, Peter W. Kaplan, AND Terrie E. Taylor
Reference: 
Am J Trop Med Hyg 2010;82 231-234

The diagnosis of cerebral malaria (CM) is difficult to confirm in endemic regions with limited neurodiagnostics. Accurate diagnoses are critical for trials and outcomes studies.

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Cost-effectiveness analysis of rapid diagnostic test, microscopy and syndromic approach in the diagnosis of malaria in Nigeria: implications for scaling-up deployment of ACT

November 26, 2009 - 12:49 -- Ingeborg van Schayk
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Author(s): 
Benjamin SC Uzochukwu, Eric N Obikeze, Obinna E Onwujekwe, Chima A Onoka, Ulla K Griffiths
Reference: 
Malaria Journal 2009, 8:265 (23 November 2009)

Paper comparing different diagnostic methods used in Nigeria, from a cost-effectiveness view point .

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