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Comparing metabolic network models based on genomic and automatically inferred enzyme information from Plasmodium and its human host to define drug targets in silico

December 20, 2010 - 09:48 -- Patrick Sampao
Segun Fatumo, Kitiporn Plaimas, Ezekiel Adebiyi, Rainer König
Infection, Genetics and Evolution, Volume 11, Issue 1, January 2011, Pages 201-208

Comparing the modeling results with a comprehensive list of known drug targets for P. falciparum, showed that we had the best discovery success with a network model consisting only of enzymes from the parasite alone which coding genes were known.

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