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The distribution of insecticide resistance in Anopheles gambiae s.l. populations from Cameroon: an update

October 25, 2009 - 17:32 -- Bart G.J. Knols
Author(s): 
Hamadou N.M. et al.
Reference: 
Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 103, Issue 11, November 2009, Pages 1127-1138, doi:10.1016/j.trstmh.2008.11.018

Insecticides are a key component of vector-based malaria control programmes in Cameroon. As part of ongoing resistance surveillance efforts, Anopheles gambiae s.l. female mosquitoes were exposed to organochlorine (DDT), a carbamate (bendiocarb), an organophosphate (malathion), and three pyrethroids (deltamethrin, lambda-cyhalothrin and permethrin) in WHO bioassay test kits.

Carbamate and organophosphorous compounds could thus be used as alternatives in locations in Cameroon where pyrethroid-resistant populations are found.

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Insecticide resistance and its association with target-site mutations in natural populations of Anopheles gambiae from eastern Uganda

October 25, 2009 - 17:27 -- Bart G.J. Knols
Author(s): 
Urvashi Ramphul, Thomas Boase, Chris Bass, Loyce M. Okedi, Martin J. Donnelly, Pie Müller
Reference: 
Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 103, Issue 11, November 2009, Pages 1121-1126, doi:10.1016/j.trstmh.2009.02.014

Insecticide resistance in Anopheles gambiae threatens the success of malaria vector control programmes in sub-Saharan Africa. In order to manage insecticide resistance successfully, it is essential to assess continuously the target mosquito population. Here, we collected baseline information on the distribution and prevalence of insecticide resistance and its association with target-site mutations in eastern Uganda.

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