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ITN

Human Antibody Response to Anopheles gambiae Saliva: An Immuno-Epidemiological Biomarker to Evaluate the Efficacy of Insecticide-Treated Nets in Malaria Vector Control

July 5, 2010 - 07:07 -- Patrick Sampao
Author(s): 
Papa M., Anne P., et al.
Reference: 
Am J Trop Med Hyg, Jul 2010; 83: 115 - 121.

This study investigates a potential immunological marker, based on human antibody responses to Anopheles saliva, as a new indicator to evaluate the efficacy of insecticide-treated nets (ITNs).

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Open Access | Intermittent preventive treatment in infants for the prevention of malaria in rural Western Kenya: a randomized, double-blind placebo-controlled trial

April 8, 2010 - 07:00 -- Kabogo Ndegwa
Author(s): 
FO Odhiambo, MJ Hamel, J Williamson, K Lindblade, FO ter Kuile, E Peterson, P Otieno, S Kariuki, J Vulule, L Slutsker, RD Newman
Reference: 
PLoS One (2010) 5: e10016.

IPTi with long-acting regimens provide protection against clinical malaria for up to 8 weeks even in the presence of high ITN coverage, and that the prophylactic rather than the treatment effect of IPTi appears central to its protective efficacy.

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Open Access | Interactions between Age and ITN Use Determine the Risk of Febrile Malaria in Children

December 24, 2009 - 12:50 -- Ingeborg van Schayk
Author(s): 
Philip Bejon, Edna Ogada, Norbert Peshu, Kevin Marsh
Reference: 
PLoS ONE 4(12): e8321

These data on age interactions with ITN use suggest that larger scale studies on the long term individual outcomes should be undertaken if the policy of targeted ITN use for vulnerable groups is to continue.

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Predicting the impact of insecticide-treated bed nets on malaria transmission: the devil is in the detail

November 26, 2009 - 11:41 -- Ingeborg van Schayk
Author(s): 
Weidong Gu, Robert J Novak
Reference: 
Malaria Journal 2009, 8:256 (16 November 2009)

This study highlights that increased ITN coverage led to significant reduction in risk exposure and malaria incidence only when treated nets yielded high killing effects. It is necessary to test efficacy of treated nets on local dominant vector mosquitoes, at least in laboratory, for monitoring and evaluation of ITN programmes.

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Preliminary examination of integrated vector management in a tropical rainforest area of Cameroon

October 25, 2009 - 17:09 -- Bart G.J. Knols
Author(s): 
G.A. Matthews, H.M. Dobson, P.B. Nkot, T.L. Wiles, M. Birchmore
Reference: 
Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 103, Issue 11, November 2009, Pages 1098-1104, doi:10.1016/j.trstmh.2009.03.003

In a malaria-endemic area, a pilot study examined different mosquito control interventions applied to entire villages to assess their impact on vectors, malaria incidence and the quality of life of the communities. Malaria incidence several months after treatments was not significantly different from pre-treatment levels. Blackfly adult populations were reduced for several weeks following larvicide application but recovered when treatment was halted.

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