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mass spectrometry

Investigating Alternative Acidic Proteases for H/D Exchange Coupled to Mass Spectrometry: Plasmepsin 2 but not Plasmepsin 4 Is Active Under Quenching Conditions

January 14, 2010 - 18:12 -- Kabogo Ndegwa
Author(s): 
Julien Marcouxa, b, Eric Thierrya, Corinne Vivèsb, Luca Signora, Franck Fieschib and Eric Foresta
Reference: 
Journal of the American Society for Mass Spectrometry, Volume 21, Issue 1, January 2010, Pages 76-79

Structural studies of proteins by hydrogen/deuterium exchange coupled to mass spectrometry (DXMS) require the use of proteases working at acidic pH and low temperatures.

Medical Condition: 
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