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mass spectrometry

Investigating Alternative Acidic Proteases for H/D Exchange Coupled to Mass Spectrometry: Plasmepsin 2 but not Plasmepsin 4 Is Active Under Quenching Conditions

January 14, 2010 - 18:12 -- Kabogo Ndegwa
Julien Marcouxa, b, Eric Thierrya, Corinne Vivèsb, Luca Signora, Franck Fieschib and Eric Foresta
Journal of the American Society for Mass Spectrometry, Volume 21, Issue 1, January 2010, Pages 76-79

Structural studies of proteins by hydrogen/deuterium exchange coupled to mass spectrometry (DXMS) require the use of proteases working at acidic pH and low temperatures.

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