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histopathology

Expression, Immunogenicity, Histopathology, and Potency of a Mosquito-based Malaria Transmission-blocking Recombinant Vaccine

February 8, 2012 - 07:46 -- Patrick Sampao
Author(s): 
D.K. Mathias, J.L. Plieskatt, R.R. Dinglasan, et al.
Reference: 
Infect. Immun. volume 80, issue 2 ,February 2012

MalariaWorldWe have developed a scalable, high-yield E. coli expression and purification platform for the recombinant AnAPN1 TBV antigen and report on its marked vaccine potency and immunogenicity, its capacity for eliciting transmission-blocking antibodies, and its apparent lack of immunization-associated histopathologies in a small animal model.

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Diagnosis of Gestational, Congenital, and Placental Malaria in Colombia: Comparison of the Efficacy of Microscopy, Nested Polymerase Chain Reaction, and Histopathology

June 2, 2011 - 14:56 -- Patrick Sampao
Author(s): 
Ivón M. Campos, Mary L. Uribe, Carolina Cuesta, Alexander Franco-Gallego, Jaime Carmona-Fonseca, and Amanda Maestre
Reference: 
Am J Trop Med Hyg 2011 84:929-935

We designed a study to compare the technical and the operational-economical performances of light microscopy (LM), nested polymerase chain reaction (nPCR), and histopathology (HP).

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In vivo study of human Plasmodium knowlesi in Macaca fascicularis

January 14, 2010 - 18:04 -- Kabogo Ndegwa
Author(s): 
F. Anderios, A. NoorRain, I. Vythilingam
Reference: 
Experimental Parasitology, Volume 124, Issue 2, February 2010, Pages 181-189

In this study Macaca fascicularis was used as a model to understand the host response to P. knowlesi using parasitological and haematological parameters.

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