The world's scientific and social network for malaria professionals
Subscribe to free Newsletter | 10651 malaria professionals are enjoying the free benefits of MalariaWorld today

apoptosis

Not Open Access | Low-Level Plasmodium falciparum Blood-Stage Infection Causes Dendritic Cell Apoptosis and Dysfunction in Healthy Volunteers

July 12, 2012 - 07:45 -- Patrick Sampao
Author(s): 
Tonia Woodberry, Gabriela Minigo, Kim A. Piera, Fiona H. Amante, Alberto Pinzon-Charry, Michael F. Good, J. Alejandro Lopez, Christian R. Engwerda, James S. McCarthy and Nicholas M. Anstey
Reference: 
J Infect Dis. (2012) 206 (3): 333-340

MalariaWorldThese findings may explain in part the inadequate development of immunity to blood-stage malaria infection.

Technology: 
Person: 

Effects of Plasmodium berghei on thymus: High levels of apoptosis and premature egress of CD4+CD8+ thymocytes in experimentally infected mice

September 15, 2011 - 14:10 -- Patrick Sampao
Author(s): 
Carolina Francelin, Luciana Campos Paulino, Jacy Gameiro, Liana Verinaud
Reference: 
Volume 216, Issue 10, October 2011, Pages 1148-1154

In order to verify if an accelerated emigration of thymic cells to the peripheral lymphoid organs was also occurring we analyzed the spleen and mesenteric lymph nodes from control and infected mice.

Technology: 
Medical Condition: 

Open Access | Inhibition of Plasmodium falciparum Field Isolates-Mediated Endothelial Cell Apoptosis by Fasudil: Therapeutic Implications for Severe Malaria

October 18, 2010 - 09:12 -- Patrick Sampao
Author(s): 
Estelle S., Ulrick B., et al.
Reference: 
PLoS ONE 5(10): e13221.

We therefore assessed herein whether Fasudil would have a similar efficiency on P. falciparum taken directly from malaria patients using contact and non-contact experiments. Seven (23.3%) of 30 PRBC preparations from different patients were apoptogenic, four (13.3%) acting by cytoadherence and three (10%) via soluble factors.

Technology: 

Open Access | Hemozoin (Malarial Pigment) Directly Promotes Apoptosis of Erythroid Precursors

January 10, 2010 - 15:13 -- Ingeborg van Schayk
Author(s): 
Abigail A. Lamikanra, Michel Theron, Taco W. A. Kooij, David J. Roberts
Reference: 
PLoS ONE 4(12): e8446

Severe malarial anemia is the most common syndrome of severe malaria in endemic areas.

Medical Condition: 
Subscribe to RSS - apoptosis