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MSP3

Toward the Rational Design of a Malaria Vaccine Construct Using the MSP3 Family as an Example: Contribution of Antigenicity Studies in Humans

January 10, 2010 - 14:35 -- Ingeborg van Schayk
Author(s): 
Corine G. Demanga, Lena-Juliette Daher, Eric Prieur, Catherine Blanc, Jean-Louis Pérignon, Hasnaa Bouharoun-Tayoun, and Pierre Druilhe
Reference: 
Infect. Immun. 2010;78 486-494

These results indicate that numerous regions from the MSP3 family play a role in protection and provide a rationale for the tailoring of new MSP3-derived malaria vaccines.

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Toward the Rational Design of a Malaria Vaccine Construct Using the MSP3 Family as an Example: Contribution of Immunogenicity Studies in Models

January 10, 2010 - 14:32 -- Ingeborg van Schayk
Author(s): 
Lena-Juliette Daher, Corine G. Demanga, Eric Prieur, Jean-Louis Pérignon, Hasnaa Bouharoun-Tayoun, and Pierre Druilhe
Reference: 
Infect. Immun. 2010;78 477-485

Plasmodium falciparum merozoite surface protein 3 (MSP3), the target of antibodies that mediate parasite killing in cooperation with blood monocytes and are associated with protection in exposed populations, is a vaccine candidate under development.

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