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malaria rapid diagnostic test

Use of real-time multiplex PCR, malaria rapid diagnostic test and microscopy to investigate the prevalence of Plasmodium species among febrile hospital patients in Sierra Leone

February 25, 2020 - 15:56 -- Open Access
Tomasz A. Leski, Chris Rowe Taitt, David A. Stenger, et al.
Malaria Journal 2020 19:84, 21 February 2020

Malaria continues to affect over 200 million individuals every year, especially children in Africa. Rapid and sensitive detection and identification of Plasmodium parasites is crucial for treating patients and monitoring of control efforts. Compared to traditional diagnostic methods such as microscopy and rapid diagnostic tests (RDTs), DNA based methods, such as polymerase chain reaction (PCR) offer significantly higher sensitivity, definitive discrimination of Plasmodium species, and detection of mixed infections. While PCR is not currently optimized for routine diagnostics, its role in epidemiological studies is increasing as the world moves closer toward regional and eventually global malaria elimination. This study demonstrates the field use of a novel, ambient temperature-stabilized, multiplexed PCR assay in a small hospital setting in Sierra Leone.

Adherence to malaria rapid diagnostic test result among healthcare workers in Sokoto metropolis, Nigeria

January 6, 2020 - 16:29 -- Open Access
Aliyu Mamman Na’uzo, Dahiru Tukur, Olufemi Ajumobi, et al.
Malaria Journal 2020 19:2, 2 January 2020

Presumptive diagnosis and prescription of anti-malarial medicines to malaria rapid diagnostic test (RDT)-negative patients is a common practice among health care workers (HCWs) in Nigeria. There is paucity of data on HCWs adherence to RDT result in Sokoto metropolis, Nigeria. The study was conducted to determine HCWs adherence to malaria test result and the influencing factors.

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