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Tamoxifen

Tamoxifen activity against Plasmodium in vitro and in mice

December 3, 2019 - 15:24 -- Open Access
Author(s): 
Ada Weinstock, Julio Gallego-Delgado, Cláudia Gomes, Julian Sherman, Cyrus Nikain, Sandra Gonzalez, Edward Fisher and Ana Rodriguez
Reference: 
Malaria Journal 2019 18:378, 27 November 2019

Tamoxifen is an oestrogen receptor modulator that is widely used for the treatment of early stage breast cancer and reduction of recurrences. Tamoxifen is also used as a powerful research tool for controlling gene expression in the context of the Cre/loxP site-specific recombination system in conditional mutant mice.

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