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symptomatic adolescents

Description of Plasmodium falciparum infections in central Gabon demonstrating high parasite densities among symptomatic adolescents and adults

November 26, 2019 - 14:40 -- Open Access
Rella Zoleko Manego, Erik Koehne, Andrea Kreidenweiss, Brice Nzigou Mombo, Bayode Romeo Adegbite, Lia Betty Dimessa Mbadinga, Malik Akinosho, Julian Matthewman, Ayola Akim Adegnika, Michael Ramharter and Ghyslain Mombo-Ngoma
Malaria Journal 2019 18:371, 21 November 2019

Malaria remains a public health issue, particularly in sub-Saharan Africa with special features of seriousness in young children and pregnant women. Adolescents and adults are reported to have acquired a semi-immune status and, therefore, present with low parasitaemia. Children are understood to present with a much higher parasitaemia and severe malaria. It is a concern that effective malaria control programmes targeting young children may lead to a delay in the acquisition of acquired immunity and, therefore, causing a shift in the epidemiology of malaria. Prevalence and parasitaemia were explored in adolescents and adults with Plasmodium falciparum infections compared to young children in the area of Lambaréné, Gabon as an indicator for semi-immunity.

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