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L1014F

Putative pleiotropic effects of the knockdown resistance (L1014F) allele on the life-history traits of Anopheles gambiae

January 12, 2022 - 23:02 -- Open Access
Author(s): 
Adandé A. Medjigbodo, Luc S. Djogbénou, Oswald Y. Djihinto, Romaric B. Akoton, Emmanuella Abbey, Rosaria M. Kakossou, Eric G. Sonounameto, Esther B. J. Salavi, Laurette Djossou and Athanase Badolo
Reference: 
Malaria Journal 2021 20:480, 20 December 2021

Existing mechanisms of insecticide resistance are known to help the survival of mosquitoes following contact with chemical compounds, even though they could negatively affect the life-history traits of resistant malaria vectors. In West Africa, the knockdown resistance mechanism kdrR (L1014F) is the most common. However, little knowledge is available on its effects on mosquito life-history traits. The fitness effects associated with this knockdown resistance allele in Anopheles gambiae sensu stricto (s.s.) were investigated in an insecticide-free laboratory environment.

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