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Peruvian Amazon

Malaria Situation in the Peruvian Amazon during the COVID-19 Pandemic

September 12, 2020 - 15:02 -- Open Access
Author(s): 
Torres K, Alava F, Soto-Calle V, Llanos-Cuentas A, Rodriguez H, Llacsahuanga L, Gamboa D, Vinetz J
Reference: 
Am J Trop Med Hyg. 2020 Sep 3

The Peruvian Ministry of Health reports a near absence of malaria cases in the Amazon region during the COVID-19 pandemic. However, the rapid increase in SARS-CoV-2 infections has overwhelmed the Peruvian health system, leading to national panic and closure of public medical facilities, casting doubt on how accurately malaria cases' numbers reflect reality.

Not Open Access | Temporal and micro-spatial heterogeneity in transmission dynamics of co-endemic Plasmodium vivax and Plasmodium falciparum in two rural cohort populations in the Peruvian Amazon

August 25, 2020 - 07:59 -- NOT Open Access
Author(s): 
Rosas-Aguirre A, Guzman-Guzman M, Llanos-Cuentas A, et al.
Reference: 
J Infect Dis. 2020 Aug 21:jiaa526

Malaria is highly heterogeneous; its changing malaria micro-epidemiology needs to be addressed to support malaria elimination efforts at the regional level.

Economic costs analysis of uncomplicated malaria case management in the Peruvian Amazon

April 23, 2020 - 10:24 -- Open Access
Author(s): 
Diamantina Moreno-Gutierrez, Angel Rosas-Aguirre, Philippe Beutels, et al.
Reference: 
Malaria Journal 2020 19:161, 21 April 2020

Case management is one of the principal strategies for malaria control. This study aimed to estimate the economic costs of uncomplicated malaria case management and explore the influence of health-seeking behaviours on those costs.

Guaroa Virus and Plasmodium vivax Co-Infections, Peruvian Amazon

April 6, 2020 - 08:16 -- Open Access
Author(s): 
Siles C, Elson WH, Vilcarromero S, Morrison AC, Hontz RD, Alava F, Valdivia H, Felices V, Guevara C, Jenkins S, Abente EJ, Ampuero JS
Reference: 
Emerg Infect Dis. 2020 Apr;26(4):731-737

During April–June 2014 in a malaria-endemic rural community close to the city of Iquitos in Peru, we detected evidence of Guaroa virus (GROV) infection in 14 febrile persons, of whom 6 also had evidence of Plasmodium vivax malaria. Cases were discovered through a long-term febrile illness surveillance network at local participating health facilities.

Anti-MSP-10 IgG indicates recent exposure to Plasmodium vivax infection in the Peruvian Amazon

November 27, 2019 - 16:02 -- Open Access
Author(s): 
Rosas-Aguirre A, Patra KP, Vinetz JM, et al.
Reference: 
JCI Insight. 2019 Nov 26. pii: 130769

Serological tools for the accurate detection of recent malaria exposure are needed to guide and monitor malaria control efforts. IgG responses against P. vivax and P. falciparum merozoite surface protein-10 (MSP10) were measured as a potential way to identify recent malaria exposure in the Peruvian Amazon.

Country: 

Microsatellite analysis reveals connectivity among geographically distant transmission zones of Plasmodium vivax in the Peruvian Amazon: A critical barrier to regional malaria elimination

November 25, 2019 - 16:02 -- Open Access
Author(s): 
Paulo Manrique, Julio Miranda-Alban, Jhonatan Alarcon-Baldeon, Roberson Ramirez, Gabriel Carrasco-Escobar, Henry Herrera, Mitchel Guzman-Guzman, Angel Rosas-Aguirre, Alejandro Llanos-Cuentas, Joseph M. Vinetz, Ananias A. Escalante, Dionicia Gamboa
Reference: 
PLoS Negl Trop Dis 13(11): e0007876

Despite efforts made over decades by the Peruvian government to eliminate malaria, Plasmodium vivax remains a challenge for public health decision-makers in the country. The uneven distribution of its incidence, plus its complex pattern of dispersion, has made ineffective control measures based on global information that lack the necessary detail to understand transmission fully. In this sense, population genetic tools can complement current surveillance. This study describes the genetic diversity and population structure from September 2012 to March 2015 in three geographically distant settlements, Cahuide (CAH), Lupuna (LUP) and Santa Emilia (STE), located in the Peruvian Amazon.

Medical Condition: 
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