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Determinants of primaquine and carboxyprimaquine exposures in children and adults with Plasmodium vivax malaria

August 17, 2021 - 16:25 -- Open Access
Chu CS, Watson JA, Phyo AP, Win HH, Yotyingaphiram W, Thinraow S, Soe NL, Aung AA, Wilaisrisak P, Kraft K, Imwong M, Hanpithakpong W, Blessborn D, Tarning J, Proux S, Ling C, Nosten FH, White NJ
Antimicrob Agents Chemother. 2021 Aug 16:AAC0130221

Primaquine is the only widely available drug for radical cure of Plasmodium vivax malaria. There is uncertainty whether the pharmacokinetic properties of primaquine are altered significantly in childhood or not.

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