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clinical drug

NOT Open Access | Antimalarial drug discovery: from quinine to the most recent promising clinical drug candidates

August 11, 2021 - 14:55 -- NOT Open Access
Author(s): 
Tisnerat C, Dassonville-Klimpt A, Gosselet F, Sonnet P
Reference: 
Curr Med Chem. 2021 Aug 3

Malaria is a tropical threatening disease caused by Plasmodium parasites, resulting in 409,000 deaths in 2019. The delay of mortality and morbidity has been compounded by the widespread of drug resistant parasites from Southeast Asia since two decades. The emergence of artemisinin-resistant Plasmodium in Africa, where most cases are accounted, highlights the urgent need for new medicines.

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