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vitex negundo L.

NOT Open Access | Evaluation of ethnopharmacologically selected Vitex negundo L. for In vitro antimalarial activity and secondary metabolite profiling

July 20, 2021 - 13:31 -- NOT Open Access
Dwivedi MK, Shukla R, Sharma NK, Manhas A, Srivastava K, Kumar N, Singh PK
J Ethnopharmacol. 2021 Jul 15;275:114076

Limited drugs, rise in drug resistance against frontline anti-malarial drugs, non-availability of efficacious vaccines and high cost of drug development hinders malaria intervention programs. Search for safe, effective and affordable plant based anti-malarial agents, thus becomes crucial and vital in the current scenario. The Vitex negundo L. is medicinal plant possessing a variety of pharmaceutically important compounds. The plant is used traditionally worldwide for the treatment of malaria including India and Malaysia by the indigenous tribes. In vitro studies have reported the anti-malarial use of the plant in traditional medicinal systems.

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