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culicifacies

NOT Open Access | Hemocyte RNA-Seq analysis of Indian malarial vectors Anopheles stephensi and Anopheles culicifacies: from similarities to differences

July 6, 2021 - 13:32 -- NOT Open Access
Author(s): 
Rani J, Chauhan C, Das De T, Kumari S, Sharma P, Tevatiya S, Patel K, Mishra AK, Pandey KC, Singh N, Dixit R
Reference: 
Gene. 2021 Jul 2:145810

Anopheles stephensi and Anopheles culicifacies are dominant malarial vectors in urban and rural India, respectively. Both species carry significant biological differences in their behavioral adaptation and immunity, but the genetic basis of these variations are still poorly understood. Here, we uncovered the genetic differences of immune blood cells, that influence several immune-physiological responses. We generated, analyzed and compared the hemocyte RNA-Seq database of both mosquitoes. A total of 5,837,223,769 assembled bases collapsed into 7,595 and 3,791 transcripts, originating from hemocytes of laboratory-reared 3-4 days old naïve (sugar-fed) mosquitoes, Anopheles stephensi and Anopheles culicifacies respectively.

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