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A cost analysis to address issues of budget constraints on the implementation of the indoor residual spray programme in two districts of Maputo Province, Mozambique

January 7, 2021 - 11:52 -- Open Access
Neide Canana
Malaria Journal 2021 20:8, 6 January 2021

It is frequently said that funding is essential to ensure optimal results from a malaria intervention control. However, in recent years, the capacity of the government of Mozambique to sustain the operational cost of indoor residual spraying (IRS) is facing numerous challenges due to restrictions of the Official Development Assistance. The purpose of the study was to estimate the cost of IRS operationalization in two districts of Maputo Province (Matutuíne and Namaacha) in Mozambique. The evidence produced in this study intends to provide decision-makers with insight into where they need to pay close attention in future planning in order to operationalize IRS with the existent budget in the actual context of budget restrictions.

Field performance of ultrasensitive and conventional malaria rapid diagnostic tests in southern Mozambique

December 8, 2020 - 10:48 -- Open Access
Beatriz Galatas, Alfredo Mayor, Himanshu Gupta, Núria Balanza, Ihn Kyung Jang, Lidia Nhamussua, Wilson Simone, Pau Cisteró, Arlindo Chidimatembue, Humberto Munguambe, Francisco Saúte, Pedro Aide and Quique Bassat
Malaria Journal 2020 19:451, 7 December 2020

An ultrasensitive malaria rapid diagnostic test (RDT) was recently developed for the improved detection of low-density Plasmodium falciparum infections. This study aimed to compare the diagnostic performance of the PfHRP2-based Abbott Malaria Ag P. falciparum ultrasensitive RDT (uRDT) to that of the conventional SD-Bioline Malaria Ag P. falciparum RDT (cRDT) when performed under field conditions.

Geostatistical analysis and mapping of malaria risk in children of Mozambique

November 10, 2020 - 15:02 -- Open Access
Ejigu BA
PLoS One. 2020 Nov 9;15(11):e0241680

Malaria remains one of the most prevalent infectious diseases in the tropics and subtropics, and Mozambique is not an exception. To design geographically targeted and effective intervention mechanisms of malaria, an up-to-date map that shows the spatial distribution of malaria is needed. This study analyzed 2018 Mozambique Malaria Indicator Survey using geostatistical methods to: i) explore individual, household, and community-level determinants of malaria in under-five children, ii) prepare a malaria prevalence map in Mozambique, and iii) produce prediction prevalence maps and exceedence probability across the country.

Effect of mass dihydroartemisinin-piperaquine administration in southern Mozambique on the carriage of molecular markers of antimalarial resistance

October 21, 2020 - 08:34 -- Open Access
Gupta H, Galatas B, Mayor A, et al.
PLoS One. 2020 Oct 19;15(10):e0240174

Mass drug administration (MDA) can rapidly reduce the burden of Plasmodium falciparum (Pf). However, concerns remain about its contribution to select for antimalarial drug resistance.

A multiphase program for malaria elimination in southern Mozambique (the Magude project): A before-after study

August 18, 2020 - 15:00 -- Open Access
Galatas B, Saúte F, Martí-Soler H, Aide P, et al.
PLoS Med. 2020 Aug 14;17(8):e1003227

Malaria eradication remains the long-term vision of the World Health Organization (WHO). However, whether malaria elimination is feasible in areas of stable transmission in sub-Saharan Africa with currently available tools remains a subject of debate. This study aimed to evaluate a multiphased malaria elimination project to interrupt Plasmodium falciparum malaria transmission in a rural district of southern Mozambique.

Moving towards malaria elimination in southern Mozambique: Cost and cost-effectiveness of mass drug administration combined with intensified malaria control

July 7, 2020 - 13:41 -- Open Access
Cirera L, Galatas B, Alonso S, Paaijmans K, Mamuquele M, Martí-Soler H, Guinovart C, Munguambe H, Luis F, Nhantumbo H, Montañà J, Bassat Q, Candrinho B, Rabinovich R, Macete E, Aide P, Alonso P, Saúte F, Sicuri E
PLoS ONE 15(7): e0235631

As new combinations of interventions aiming at interrupting malaria transmission are under evaluation, understanding the associated economic costs and benefits is critical for decision-making. This study assessed the economic cost and cost-effectiveness of the Magude project, a malaria elimination initiative implemented in a district in southern Mozambique (i.e. Magude) between August 2015–June 2018. This project piloted a combination of two mass drug administration (MDA) rounds per year for two consecutive years, annual rounds of universal indoor residual spraying (IRS) and a strengthened surveillance and response system on the back of universal long-lasting insecticide treated net (LLIN) coverage and routine case management implemented by the National Malaria Control Program (NMCP). Although local transmission was not interrupted, the project achieved large reductions in the burden of malaria in the target district.

Monitoring the durability of the long-lasting insecticidal nets MAGNet and Royal Sentry in three ecological zones of Mozambique

June 22, 2020 - 16:32 -- Open Access
Ana Paula Abílio, Emmanuel Obi, Albert Kilian, et al.
Malaria Journal 2020 19:209, 17 June 2020

Malaria prevention with long-lasting insecticidal nets (LLINs) has seen a tremendous scale-up in sub-Saharan Africa in the last decade. To sustain this success, it is important to understand how long LLINs remain in the households and continue to protect net users, which is termed durability. This information is needed to decide the appropriate timing of LLIN distribution and also to identify product(s) that may be underperforming relative to expectations. Following guidance from the U.S. President’s Malaria Initiative, durability monitoring of polyethylene 150-denier LLIN (Royal Sentry® and MAGNet®) distributed during a 2017 mass campaign in Mozambique was implemented in three ecologically different sites: Inhambane, Tete, and Nampula.

Demographic and health community-based surveys to inform a malaria elimination project in Magude district, southern Mozambique

May 7, 2020 - 11:30 -- Open Access
Galatas B, Nhacolo A, Sacoor C, et al.
BMJ Open. 2020 May 5;10(5):e033985

A Demographic and Health Platform was established in Magude in 2015, prior to the deployment of a project aiming to evaluate the feasibility of malaria elimination in southern Mozambique, named the Magude project. This platform aimed to inform the design, implementation and evaluation of the Magude project, through the identification of households and population; and the collection of demographic, health and malaria information.

Quality of malaria data in public health facilities in three provinces of Mozambique

April 21, 2020 - 13:29 -- Open Access
Colborn JM, Zulliger R, Plucinski MM, et al.
PLoS ONE 15(4): e0231358

Malaria data reported through Mozambique’s routine health information system are used to guide the implementation of prevention and control activities. Although previous studies have identified issues with the quality of aggregated data reported from public health facilities in the country, no studies have evaluated the quality of routine indicators recorded in health facility registries. This study addresses this issue by comparing indicators calculated from data from exit interviews and re-examinations of patients with data based on registry records from health facilities in order to measure the quality of registry data and data reporting in three provinces in Mozambique.

“We have this, with my husband, we live in harmony”: exploring the gendered decision-making matrix for malaria prevention and treatment in Nampula Province, Mozambique

March 31, 2020 - 15:59 -- Open Access
Zoe Jane-Lara Hildon, Maria Escorcio-Ymayo, Rose Zulliger, Rosario Arias de Aramburú, Nan Lewicky, Hunter Harig, Jose Braz Chidassicua, Carol Underwood, Liliana Pinto and Maria Elena Figueroa
Malaria Journal 2020 19:133, 30 March 2020

Conceptualizing gender dynamics and ways of bridging entrenched gender roles will contribute to better health promotion, policy and planning. Such processes are explored in relation to malaria in Mozambique.


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