Bone Marrow and Hypnozoite-Independent Plasmodium vivax Malarial Recurrences
As shown by the record of historical events listed in Table 1 in a recent review of biological concepts in recurrent vivax malaria, the question of a hypnozoite-independent, non-circulating origin(s) of recurrences was first raised approximately 7 years ago. (Link to the paper and Table 1 [click here]). More specifically, parasites in bone marrow as a possible contributing source are discussed in this 2018 article, the matter having initially been debated in a 2017 publication cited therein.
