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sub-Saharan Central Africa

Plasmodium vinckei genomes provide insights into the pan-genome and evolution of rodent malaria parasites

April 29, 2021 - 08:08 -- Open Access
Author(s): 
Ramaprasad A, Klaus S, Douvropoulou O, Culleton R, Pain A
Reference: 
BMC Biol. 2021 Apr 23;19(1):69

Rodent malaria parasites (RMPs) serve as tractable tools to study malaria parasite biology and host-parasite-vector interactions. Among the four RMPs originally collected from wild thicket rats in sub-Saharan Central Africa and adapted to laboratory mice, Plasmodium vinckei is the most geographically widespread with isolates collected from five separate locations. However, there is a lack of extensive phenotype and genotype data associated with this species, thus hindering its use in experimental studies.

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