The present study is aimed to elucidate the effects of concomitant application of irradiated carrageenan (IC) oligomers and salicylic acid (SA) on Artemisia annua L. varieties, viz. "CIM-Arogya" (tolerant) and "Jeevan Raksha" (sensitive) exposed to arsenic (As) stress. Artemisia annua has been known for its sesqui-terpene molecule artemisinin, which is useful in curing malaria. The two compounds, IC and SA, have been established as effective plant growth-promoting molecules for several agricultural and horticultural crops. To test the stress tolerance providing efficacy of IC and SA, the characterization of various physiological and biochemical parameters, growth as well as yield attributes was done in the present experiment.