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TACT

Deploying triple artemisinin-based combination therapy (TACT) for malaria treatment in Africa: ethical and practical considerations

March 3, 2021 - 15:45 -- Open Access
Author(s): 
Paulina Tindana, Freek de Haan, Chanaki Amaratunga, Mehul Dhorda, Rob W. van der Pluijm, Arjen M. Dondorp and Phaik Yeong Cheah
Reference: 
Malaria Journal 2021 20:119, 27 February 2021

Malaria remains a major cause of morbidity and mortality in Africa, particularly in children under five years of age. Availability of effective anti-malarial drug treatment is a cornerstone for malaria control and eventual malaria elimination. Artemisinin-based combination therapy (ACT) is worldwide the first-line treatment for uncomplicated falciparum malaria, but the ACT drugs are starting to fail in Southeast Asia because of drug resistance.

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