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Within‐household clustering of genetically related Plasmodium falciparum infections in a moderate transmission area of Uganda

February 3, 2021 - 15:48 -- Open Access
Author(s): 
Jessica Briggs, Alison Kuchta, Bryan Greenhouse, et al.
Reference: 
Malaria Journal 2021 20:68, 2 February 2021

Evaluation of genetic relatedness of malaria parasites is a useful tool for understanding transmission patterns, but patterns are not easily detectable in areas with moderate to high malaria transmission. To evaluate the feasibility of detecting genetic relatedness in a moderate malaria transmission setting, relatedness of Plasmodium falciparum infections was measured in cohort participants from randomly selected households in the Kihihi sub-county of Uganda (annual entomological inoculation rate of 27 infectious bites per person).

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